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Therapeutic Advances in Thrombosis
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Table of Contents

Contributors, vii


Foreword, x


Preface, xi


1 Arterial thrombosis: a brief overview, 1

Lina Badimon and Valentin Fuster


2 Aspirin, 12

Carlo Patrono




3 Platelet ADP P2Y12 inhibitors: thienopyridines, 26

Joseph D. Foley III and David J. Moliterno


4 Platelet ADP P2Y12 inhibitors: nonthienopyridines, 47

Joseph D. Foley III and David J. Moliterno


5 Cilostazol and dipyridamole: more than weak inhibition of
platelets, 62

Wolfgang G. Eisert


6 Interrelationship of thrombin and platelets: the protease
activated receptor-1, 71

Matthew E. Wiisanen and David J. Moliterno


7 Glycoprotein IIb/IIIa inhibitors, 87

Marco Valgimigli and Elisa Cangiano


8 Unfractionated heparin and low molecular weight heparin in
ischemic heart disease, 111

Zafar Iqbal, Omar Hasan, and Marc Cohen


9 Pentasaccharide derivatives, 128

Antonio Gutierrez, Pierluigi Tricoci, and John H.P.
Alexander


10 Intravenous direct thrombin inhibitors, 150

Femi Philip and A. Michael Lincoff


11 Vitamin K antagonists, 166

Freek W.A. Verheugt


12 Oral direct thrombin inhibitors and oral factor Xa
inhibitors, 180

Steen Husted and Lars Wallentin


13 Thrombolytic therapy and concomitant antithrombotic
therapies, 189

Peter R. Sinnaeve and Frans J. Van de Werf


14 Antithrombotic therapy in ST-segment elevation myocardial
infarction, 205

Kurt Huber, Raffaele De Caterina, and Steen Dalby
Kristensen


15 Antithrombotic therapy in non?ST-segment elevation
acute coronary syndromes, 213

Georgios J. Vlachojannis, Vijayalakshmi Kunadian, Joseph M.
Sweeny, and Roxana Mehran


16 Antithrombotic strategies in patients undergoing elective
percutaneous coronary intervention, 236

Sunil V. Rao and E. Magnus Ohman


17 Antithrombotic management in patients with prosthetic valves,
246

Eric G. Butchart and Raffaele De Caterina


18 Stroke: thrombolysis and antithrombotic therapy, 272

L. Creed Pettigrew and Michael R. Dobbs


19 Atrial fibrillation: current and forthcoming antithrombotic
therapies, 285

Raffaele De Caterina and Giulia Renda


20 Venous thromboembolism: pathophysiology, diagnosis, and
prophylaxis, 306

Marco P. Donadini, Walter Ageno, and Alexander G. Turpie


21 Antithrombotic therapy in venous thrombosis and pulmonary
embolism, 317

Marcello Di Nisio and Harry R. Büller


22 Prevention and treatment of venous and arterial thrombosis in
patients with specific conditions: diabetes, hypercoagulable
states, pregnancy, and renal insufficiency, 327

Meyer Michel Samama, Jacqueline Conard, and Grigoris
Gerotziafas


23 Genetics of the response to antithrombotic drugs and the need
for monitoring, 357

Jean-Philippe Collet, Gilles Montalescot, and
Jean-Sébastien Hulot


Index, 378

About the Author

David Moliterno, M.D, co-director of the Gill Heart Institute, professor of Internal Medicine and division chief of Cardiovascular Medicine at the University of Lexington, Kentucky. He is also inaugurated as the American College of Cardiology Governor of the Kentucky chapter for the years 2007-2010.
He has 189 articles published as listed on PubMed and is the author of the following books: Therapeutic Strategies in Thrombosis 1E; 900 Questions: An Interventional Cardiology Board Review.
Raffaele De Caterina, MD, Institute of Cardiology, "G. d'Annunzio" University, Chieti, Italy.
He has 261 articles published as listed on PubMed and is the author of the following books: Therapeutic Strategies in Thrombosis 1E; Endothelial Dysfunctions and Vascular Disease.
Steen Dalby Kristensen, Department of Cardiology, Aarhus University Hospital, Aarhus N, Denmark.
He has 91 articles published as listed on PubMed and is the author of the following books: Therapeutic Strategies in Thrombosis 1E.

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