Table of Contents

Introduction to Hematology 1. An Overview of Clinical Laboratory Hematology NEW! 2. Safety in the Hematology Laboratory 3. Specimen Collection 4. Care and Use of the Microscope 5. Quality Assurance Part II: Hematopoiesis 6. Morphology and Function of Cellular Components 7. Hematopoietic Theory 8. Erythrocyte Production and Destruction 9. Metabolism of the Erythrocyte 10. Hemoglobin Metabolism 11. Iron Metabolism 12. Leukopoiesis 13. Platelet Production, Structure, and Function Part III: Routine Laboratory Evaluation of Blood Cells 14. Routine Testing in Hematology 15. Examination of the Peripheral Blood Smear and Correlation with the Complete Blood Count 16. Bone Marrow Overview Part IV: Body Fluid Examination 17. Body Fluids in the Hematology Laboratory Part V: Erythrocyte Disorders 18. Anemias: RBC Morphology and Approach to Diagnosis 19. Disorders of Iron and Heme Metabolism 20. Anemias Caused by Defects of DNA Metabolism 21. Bone Marrow Failure 22. Introduction to Increased Destruction of Erythrocytes 23. Intracorpuscular Defects Leading to Increased Erythrocyte Destruction 24. Extracorpuscular Defects leading to Increased Erythrocyte Destruction--Nonimmune Causes 25. Extracorpuscular Defects leading to Increased Erythrocyte Destruction--Immune Causes 26. Hemoglobinopathies (Structural Defects in Hemoglobin) 27. Thalassemias Part VI: Leukocyte Disorders 28. Morphologic and Distributive Leukocyte Disorders 29. Introduction to Leukocyte Neoplasms 30. Cytochemistry 31. Cytogenetics 32. Molecular Diagnostics in the Clinical Laboratory 33. Flow Cytometric Analysis in Hematologic Disorders 34. Myeloproliferative Disorders 35. Myelodysplastic Syndromes 36. Acute Leukemias 37. Mature Lymphoid Neoplasms Part VII: Hematology in Selected Populations 38. Hematology in Selected Populations NEW! Part VIII: Cell Counting Automation 39. Cell Counting Automation Part IX: Hemostasis and Thrombosis 40. Normal Hemostasis and Coagulation 41. Hemorrhagic Coagulation Disorders 42. Thrombosis Risk Testing 43. Thrombocytopenia and Thrombocytosis 44. Qualitative Disorders of Platelets 45. Evaluation of Hemostasis 46. Monitoring Anticoagulant Therapy NEW! 47. Coagulation Instrumentation Appendix: Answers to Review Questions Glossary Index

About the Author

Dr. George Fritsma manages www.fritsmafactor.com, "The Fritsma Factor, Your Interactive Hemostasis Resource," an educational blog supported by Precision BioLogic Inc, Dartmouth, Nova Scotia. Dr. Fritsma also consults for the Laboratory Solutions Program for Developing Nations, supported by BioMedica Diagnostics, Inc., Windsor, Nova Scotia. He is a consultant for the Laboratory Medicine Division of the Pathology Department, University of Alabama at Birmingham School of Medicine, where he provides lectures for pathology residents and for hematology fellows. He is an adjunct Associate Professor for Michigan State and Rutgers University. George chairs the American Association for Clinical Chemistry Press Board and is a consulting editor for the Clinical Laboratory Science journal and is a member of the International Society on Thrombosis and Hemostasis and the International Society for Laboratory Hematology.