Table of Contents

Proteins of Iron Homeostasis.- Cellular Iron Physiology.- Regulation of Cellular Iron Metabolism in Mammalian Cells.- Concentrating, Storing and Detoxifying Iron: The Ferritins and Hemosiderin.- Iron Nutrition.- Intestinal Iron Absorption.- Plasma Iron and Iron Delivery to the Tissues.- Iron Salvage Pathways.- Molecular Regulation of Systemic Iron Metabolism.- Erythroid Iron Metabolism.- Iron and the Reticuloendothelial System.- Iron and the Immune System.- Iron Deficiency.- The Liabilities of Iron Deficiency.- The Anemia of Inflammation and Chronic Disease.- Disorders of Red Cell Production and the Iron-Loading Anemias.- The Pathology of Hepatic Iron Overload.- Hepatic Pathobiology of Iron Overload.- HFE-Associated Hereditary Hemochromatosis.- Non-HFE Hemochromatosis.- Miscellaneous Iron-Related Disorders.- Iron and Liver Disease.- Neuropathology and Iron: Central Nervous System Iron Homeostasis.- Iron Metabolism in Cancer and Infection.- Estimation of Body Iron Stores.- Genetic Testing for Disorders of Iron Homeostasis.- The Properties of Therapeutically Useful Iron Chelators.- Clinical Use of Iron Chelators.- Mammalian Models of Iron Homeostasis.- Yeast Iron Metabolism.- Zebrafish Models of Heme Synthesis and Iron Metabolism.

Reviews

From the reviews:“This is a comprehensive book on all aspects of iron, an essential micronutrient in body functions. The purpose is to deliver up-to-date research on iron physiology and pathophysiology. … This book is designed for researchers, PhD nutrition students, and practitioners who focus on iron disorders.” (Amy Hess-Fischl, Doody’s Book Reviews, April, 2012)