Successful Vaccines.- Immunogenicity and Immunodominance in Antibody Responses.- Immunogen Design.- Adjuvants.- Tools to screen vaccines.- Targeting glycans on human pathogens for vaccine design.- BnAbs and highly antigenically variable pathogens.
Lars Hangartner, Ph.D.
Lars Hangartner is a molecular
biologist and immunologist whose research focuses on the humoral
response against variable pathogens, such as influenza A virus and
HIV. Moreover, he has performed basic studies on measles virus and
lymphocytic choriomeningitis virus. He is currently an associate
professor at the Scripps Research Institute in La Jolla,
California, and his present research investigates Fc/FcγR
interactions as well as epitope mapping of polyclonal antibody
response in the context of HIV vaccine development.
Dennis R. Burton, Ph.D.
Dennis Burton is the Chair and Professor in the Department of
Immunology and Microbiology, The Scripps Research Institute, La
Jolla, California, USA and James and Jessie Minor Chair in
Immunology. He is the Scientific Director of the IAVI Neutralizing
Antibody Center, Director of The Consortium for HIV/AIDS Vaccine
Development (CHAVD) at Scripps, and a member of the Ragon Institute
of MGH, MIT and Harvard, Boston, USA. His research is focused on
infectious disease, in particular the interplay of antibodies and
highly mutable viruses, notably HIV. He is interested in the
potential of broadly neutralizing antibodies to inform vaccine
design.
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