Table of Contents

Part 1 New Insights in Pathophysiology of Heart Failure: Neurohormones in Advanced Heart Failure. Recent Progress in the Natriuretic Hormone Research. Cytokines and Heart Failure: Pathophysiological Roles. Endothelial Dysfunction in Heart Failure. Apoptosis: Its Mechanism and Meaning in Heart Failure. Mechanisms of Cardioprotection with Ischemic Preconditioning. Role of NO in Myocardial Injury Induced by Oxidative Stress. Cardiac Remodeling: Role of Neovascularization in Heart Failure.- Part 2 Heart Failure and Cardiac Sudden Death: QT Prolongation Syndrome in CHF. ICD Therapy: Can they prevent sudden death in CHF patients? Arrhythmias in CHF: To treat or not to treat.- Part 3 Medical Treatment of Heart Failure: Beyond ACE Inhibitors: New Concepts of Clinical Practice Guideline For Heart Failure. AII Antagonism in Heart Failure: Evaluation of Losartan in the Elderly Trial. Beta-Blockers: Benefits and Risks from Beta-blockade Therapy. Future Prospects of Endothelin Antagonists in Heart Failure. Heart Failure: Potential Benefit of Growth Hormone Therapy. Adenosine and Cardioprotection: Its Implication in Heart Failure.- Part 4 Gene Therapy for Heart Failure: Current Status and Future Prospect: In vivo Gene Supplementation for the Therapy of Cadiomyopathy. Lessons From Beta2 Receptor Transgenic Mouse. In vivo transfection of cis element 'decoy' against NF-kappaB binding site prevents myocardial damage. Scar Tissues to Viable Myocytes.- Part 5 Surgical Treatment for Heart Failure: A New Paradigm beyond Cardiac Transplantation Treatment of Profound Heart Failure by Ventricular Assist System. Ventriculoplasty of the End-Stage Heart Failure 'Batista' operation and 'Dor' operation.

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