Life in the Habitable Zone (John D Barrow); From Clay to the Code of Life (Hyman Hartman); Stepping Up to Life (Jack W Szostak); When Cells Get Creative (Giulia Rancati and Norman Pavelka); Finding Strength in Numbers (Detlev Arendt); There and Back Again (Per Ahlberg); Conquest of the Land and Sea (Byrappa Venkatesh); A Salute to Our Placoderm Pioneers (John A Long); Warming Up to Mammals (Harris Lewin); All in the Family (Francis Thackeray); Lessons From Our Inner Neanderthal (Svante Pääbo); Wired for Intelligence (Terrence Sejnowski); Getting Smart About Learning (Atsushi Iriki); More Than Just Small Talk (Tecumseh Fitch); The Logic of Cultural Evolution (Roland Fletcher); Going with the (Information) Flow (Sander van der Leeuw); Lingo with a Life of Its Own (N J Enfield); How We Became Modern (W Brian Arthur); The Creative Destruction of Evolution (Stefan Thurner); The Challenge of the Anthropocene (J Stephen Lansing); Difficult Questions in Evolution (Eörs Szathmáry); An Evolving View on Evolution (Gerd B. Müller); The Humble View from Inside Evolution (Helga Nowotny); Epilogue (Sydney Brenner).
Sydney Brenner was born in 1927 in South Africa, where he attended
high school and medical
school; he later received his DPhil from Oxford University, UK. One
of the pioneers of modern
molecular biology, Brenner was instrumental in deciphering the
basic principles of the genetic
code. In the 1960s, together with Francis Crick, Brenner showed
that the code is composed of
non-overlapping triplets; in collaboration with François Jacob and
Matthew Meselson, he went on
to demonstrate the existence of messenger RNA.
Brenner is also known for spearheading the use of the nematode worm
Caenorhabitis elegans as
a model organism for understanding human biology. He was later
awarded the 2002 Nobel Prize
in Physiology or Medicine (with H. Robert Horvitz and John E.
Sulston) for his work in C.
elegans on the genetics of programmed cell death. In the genomic
era, Brenner developed new
methods for next generation DNA sequencing, and initiated a project
to sequence the compact
genome of the Japanese pufferfish or fugu.
Brenner is currently scientific advisor to the chairman at the
Agency of Science, Technology and
Research (A*STAR), Singapore, and an adjunct professor at the Lee
Kong Chian School of
Medicine, Nanyang Technology University, Singapore, among other
affiliations. He continues to
work on genomes and their evolution.
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