Table of Contents

Structure and Mechanism of ABC Transporters; ABCA1-Mediated HDL Formation; Bile Formation, the Enterohepatic Circulation and Cholestasis; Deciphering the Role of Human Efflux Proteins in Cellular and Tissue Permeability; The Photoreceptor ABC Transporter and Its Role in Inherited Retinal Degenerative Diseases; ABCs in Immunity - The Antigen Translocation Machinery; The ABCs of Mitochondrial Metabolic Disorders; The Role of ABCC Family Members for the Disposition of Endogenous Compounds and Drugs; ABC Transporter Mutations in Heritable Skin Diseases; CFTR, Elucidating the Basis and Influencing the Outcome of a Major Genetic Disease; Physiology and Pathology of ABCC8; Getting into the Peroxisome with the ABCD Family; ABC Transporters and Sterol Homeostasis; Hot Topics, including: Multidrug Transporters in Stem Cells and Cancer Stem Cells; Targeting Regulation of ABC Transporters; Nuclear Receptors involved in Regulating Bile Flow; Gene and Small Molecule Therapy for Cystic Fibrosis.