Table of Contents

Preface vii

Acknowledgements viii

How to Use This Book ix

List of Abbreviations x

Part 1 Basics 1

The pituitary gland 1

The thyroid 13

Bone and calcium metabolism 23

The adrenal glands 30

The reproductive system 36

The pancreas 46

Lipid abnormalities and obesity 60

The neuroendocrine system 63

Part 2 Cases 66

Case 1 A 19-year-old with abdominal pain and vomiting 66

Case 2 A 35-year-old woman with palpitation and irritability 73

Case 3 A 61-year-old man with polyuria polydipsia cough and weight loss 79

Case 4 A 44-year-old woman with visual problems 82

Case 5 A 20-year-old man with recent diagnosis of diabetes 86

Case 6 Tiredness and weight gain in a 30-year-old woman with diabetes 89

Case 7 Acute confusion in an 82-year-old with known type 2 diabetes 92

Case 8 A 42-year-old man with headaches increased sweating and sexual dysfunction 98

Case 9 Amenorrhoea in an 18-year-old 102

Case 10 A 28-year-old with tiredness and abnormal thyroid function postpartum 106

Case 11 A 33-year-old man with polyuria and polydipsia 109

Case 12 A 62-year-old man with tiredness and hyponatraemia 113

Case 13 Excess hair in a 29-year-old woman 117

Case 14 A 52-year-old woman with paroxysmal atrial fibrillation and abnormal thyroid function 120

Case 15 A 22-year-old man with hypertension 123

Case 16 A 20-year-old woman with polyuria and polydipsia 126

Case 17 A 78-year-old man with pain in the leg and knee 132

Case 18 A 32-year-old woman with a lump in the neck 135

Case 19 A 26-year-old with headaches and hypertension 139

Case 20 Sweating nausea and hand tremor in a 24-year-old woman 142

Case 21 A 19-year-old man with sexual dysfunction 146

Case 22 A 38-year-old woman with muscular aches and weakness 151

Case 23 A wrist fracture in a 56-year-old woman 154

Case 24 A 37-year-old woman with recurrent flushing 158

Case 25 A 46-year-old man with an abnormal lipid profile 161

Part 3 Self-assessment 164

MCQs 164

EMQs 169

SAQs 174

Answers 176

Index of cases by diagnosis 187

Index 189

About the Author

Ramzi Ajjan, Senior Lecturer and Consultant in Endocrinology & Diabetes, University of Leeds Medical School

Reviews

"The differential diagnosis is followed by treatment and key points. With cartoons and tables. A very didactic text, for students and physicians in training. " (Pediatric Endocrinology Reviews, June 2010)

"Ajjan covers cases from Addison's disease to osteoporosis and diabetic foot ulcer, and has a section explaining the molecular and physiological aspects of endocrinology." (Times Higher Education Supplement, May 2008)