Table of Contents

Part I: Introduction to Hematology
1. An Overview of Clinical Laboratory Hematology
2. Safety in the Hematology Laboratory
3. Blood Specimen Collection
4. Care and Use of the Microscope
5. Quality Assurance in Hematology and Hemostasis Testing
Part II: Blood Cell Production, Structure, and Function
6. Cellular Structure and Function
7. Hematopoiesis
8. Erythrocyte Production and Destruction
9. Erythrocyte Metabolism and Membrane Structure and Function
10. Hemoglobin Metabolism
11. Iron Kinetics and Laboratory Assessment
12. Leukocyte Development, Kinetics, and Function
13. Platelet Production, Structure, and Function
Part III: Laboratory Evaluation of Blood Cells
14. Manual, Semiautomated, and Point-of-Care Testing in Hematology
15. Automated Blood Cell Analysis
16. Examination of the Peripheral Blood Film and Correlation with the Complete Blood Count
17. Bone Marrow Examination
18. Body Fluid Analysis in the Hematology Laboratory
Part IV: Erythrocyte Disorders
19. Anemias. Red Blood Cell Morphology and Approach to Diagnosis
20. Disorders of Iron Kinetics and Heme Metabolism
21. Anemias Caused by Defects of DNA Metabolism
22. Bone Marrow Failure
23. Introduction to Increased Destruction of Erythrocytes
24. Intrinsic Defects Leading to Increased Erythrocyte Destruction
25. Extrinsic Defects Leading to Increased Erythrocyte Destruction - Nonimmune Causes
26. Extrinsic Defects Leading to Increased Erythrocyte Destructions - Immune Causes
27. Hemoglobinopathies (Structural Defects in Hemoglobin)
28. Thalassemias
Part V: Leukocyte Disorders
29. Nonmalignant Leukocyte Disorders
30. Cytogenetics
31. Molecular Diagnostics in the Clinical Laboratory
32. Flow Cytometric Analysis in Hematologic Disorders
33. Myeloproliferative Neoplasms
34. Myelodysplastic Syndromes
35. Acute Leukemias
36. Mature Lymphoid Neoplasms
Part VI: Hemostasis and Thrombosis
37. Normal Hemostasis and Coagulation
38. Hemorrhagic Disorders and Laboratory Assessment
39. Thrombotic Disorders and Laboratory Assessment
40. Thrombocytopenia and Thrombocytosis
41. Qualitative Disorders of Platelets and Vasculature
42. Laboratory Evaluation of Hemostasis
43. Measuring Antithrombotic Therapies
44. Hemostasis and Coagulation Instrumentation
Part VII: Hematology and Hemostasis in Selected Populations
45. Pediatric and Geriatric Hematology and Hemostasis
Appendix