Table of Contents

Life Begins with Cells - Chemical Foundations - Protein Structure and Function - From Gene to Protein: Basic Molecular Genetic Mechanisms - Biomembranes and Cell Architecture - Integrating Cells into Tissues - Transport of Ions and Small Molecules across Cell Membranes - Cellular Energetics - Molecular Genetic Techniques and Genomics - Gene and Chromosome Structure - Transcriptional Control of Gene Expression - Post-Transcriptional Controls and Nuclear Transport - Signaling at the Cell Surface - Signaling Pathways That Control Gene Activity - Integrating Signals with Gene Controls - Moving Proteins into Membranes and Organelles - Vesicular Traffic, Secretion and Endocytosis - Metabolism and Movement of Lipids - Cytoskeleton 1: Microfilaments and Intermediate Filaments - Cytoskeleton 11: Microtubules - Regulating the Eukaryotic Cell Cycle - Cell Birth. Lineage, and Death - Cancer

About the Author

HARVEY LODISH is Professor of Biology at the Massachusetts Institute of Technology and Member of the Whitehead Institute for Biomedical Research. - ARNOLD BERK is a world-famous Virologist at the University of California, Los Angeles. - PAUL MATSUDAIRA is a Member of the Whitehead Institute for Biomedical Research, Professor of Biology and Bioengineering, Massachusetts Institute of Technology, and Director of the WI/MIT BioImaging Center. - CHRIS A. KAISER is Professor of Biology and teaches genetics at the Massachusetts Institute of Technology. - MONTY KRIEGER is the Thomas D. & Virginia W. Cabot Professor in the Department of Biology at Massachusetts Institute of Technology. - MATTHEW P. SCOTT is a member of the National Academy of Sciences and teaches Developmental and Disease Mechanisms to medical students, and Developmental Biology to graduate students at Stanford University. - LAWRENCE ZIPURSKY is a Professor of Biological Chemistry and an Investigator of the Howard Hughes Medical Institute in the School of Medicine at the University of California, Los Angeles. - JAMES DARNELL is a member of the National Academy of Sciences, Vincent - Astor Professor and Head of the Molecular Cell Biology Laboratory, The Rockefeller University.