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Forensic Neuropathology, Second Edition
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Table of Contents

Pathology and Neuropathology in the Forensic Setting, J.E. Leestma and E. Whitfied Sharp

The Pathologist and the Justice System

Certification of Death

The Forensic Autopsy

The Neuropathologist’s Role in Forensic Pathology

Whom Does the Forensic Pathologist Serve?

The Problem of the Manner of Death

Issues for the Neuropathologist in the Forensic Setting

What Will I Be Asked to Do When I Testify?

Implications for the Expert of Having Given Testimony

References

Scientific Evidence and the Courts, E. Whitfield Sharp

Introduction

The Frye Standard

The Daubert Era: The Search for Reliability

The Joiner Standard

The Kumho Standard

The Federal Rules of Evidence

The Ever-Changing Face of the Admissibility Standards of Scientific and

Expert Witness Testimony

Daubert States

States Where Daubert Is Viewed as Instructive

Frye and Modified-Frye States

Rules-Based-Plus-Reliability States

Judging the Reliability of Medical Literature Using the Three R’s, or the

Reasonable Reliance Requirement, of Rule 703

A Few Basics

Conclusion

References

Forensic Aspects of Adult General Neuropathology, J.E. Leestma

Introduction

Intracranial Pathology as a Cause of Death

Vascular Diseases of the Nervous System

Tumors of the Nervous System

Infections of the Nervous System

Degenerative Diseases of the Nervous System

Diseases of White Matter

Toxic and Miscellaneous Conditions

Diseases of Peripheral Nerve

Diseases of Skeletal Muscle

References

General Forensic Neuropathology of Infants and Children, J.E. Leestma

Introduction

Brain Development

Autopsy Examination of the Developing Nervous System

Neuropathology of Perinatal Period

Cerebral Palsy

Central Nervous System Malformations

Hydrocephaly

Embolism, Thrombosis, and Hemorrhage

Disorders of Hemostasis

Toxic Conditions and the Developing Nervous System

Infectious Diseases

Intrauterine Trauma

Brain Neoplasms

The Phaecomatoses

Sudden Infant Death Syndrome (SIDS)

References

Forensic Aspects of Intracranial Equilibria, J.E. Leestma

Introduction

Cerebral Edema and the Blood-Brain Barrier

Cerebrovascular Autoregulation

Cerebrospinal Fluid: Pressure/Volume Equilibrium

Hydrocephalus

Brain Herniation

Brain Death and the Respirator Brain

References

Physical Injury to the Nervous System, J.E. Leestma and K.L. Thibault

Introduction

Biomechanics

Introduction to Biomechanics: A Primer

The Scalp

The Skull and Periosteum

The Meninges

Traumatic Injury to the Brain

Spine and Spinal Cord Injury

Glossary of Terms and Units of Measurement

References

Child Abuse: Neuropathology Perspectives, J.E. Leestma

Introduction and Historical Background

Pathology of Child Abuse

Neuropathological and Forensic Issues in Child Abuse Cases

Rib Fractures and Alleged Child Abuse

Fractures of the Long Bones and Child Abuse

Nontraumatic Forms of Child Abuse

The So-Called Shaken Baby Syndrome (SBS)

Summary

References

Gunshot and Penetrating Wounds of the Nervous System, J.E. Leestma and J.B. Kirkpatrick

Introduction

Firearms

Variations in Wounding from Different Weapons

Shotgun Wounds

Unusual or Nonweapon Firearms

Gunshot Wounds in the Civilian Population

Long-Term Consequences of Missile Wounds of the Brain and Cord

Blast Injuries and the Nervous System

Wounds of the Spinal Cord and Canal

Summary and Conclusions

References

Forensic Aspects of Complex Neural Functions, J.E. Leestma

Introduction

Epilepsy and Seizure Disorders

Cognitional Disorders

Pathological Processes Associated with Behavioral Symptoms

Perceptual Disorders

Alterations in Consciousness: Stupor and Coma

Forensic Aspects of Consciousness

Agitated Delirium

References

Index

About the Author

Chicago, IL, USA

Reviews

This new edition of the publication, which has served as a major reference source to the forensic community for over two decades, becomes available to the readers contemporaneously with several other high quality publications from the field, and it is largely assumed that such a treatise is to reflect previously established teaching concepts with inevitable apodictic flavor. Jan Leestma simply proves the opposite through this genuine effort of complete rewriting of the original text and realigns it with decades of personal experience from his busy practice as a consulting neuropathologist. The endeavor is surely re-enforced by the highly acclaimed contributors. --Ljubisa J. Dragovic, M.D., Chief Medical Examiner, Oakland County, Pontiac, Michigan, in Journal of Forensic Sciences, Vol. 55, No. 1 ! the chapters that deal with head trauma and cerebrovascular disease were particularly well written and relevant to my own practice. ! I found the book very useful and would recommend it to pathologists, coroners, as well as to clinicians called to give expert opinions in both civil and criminal courts. --Paul V. Marks, Consultant Neurosurgeon, The General Infirmary at Leeds, UK I would imagine that this book is a good neuropathology atlas too. I spent lot of time looking at the illustrative pictures, and gained much simply by looking at them. In my opinion, this book should be very useful to forensic pathologists, forensic neuropathologists, clinicians, medical examiners and law enforcement officers. --Anil Aggrawal's Internet Journal of Forensic Medicine and Toxicology ! an authoritative and comprehensive text which covers the relevant neuropathology in considerable detail. ! the broad principles will stand anyone who finds themselves acting as an expert witness in good stead. !There is a consistency in style, which is sometimes lacking from multi-author texts. --Mark Walker, Wiley Online Library

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