Table of Contents

and Basic Biology.- Vitamin D and Health: Evolution, Biologic Functions, and Recommended Dietary Intakes for Vitamin D.- Photobiology of Vitamin D.- The Functional Metabolism and Molecular Biology of Vitamin D Action.- Metabolism and Catabolism of Vitamin D, Its Metabolites and Clinically Relevant Analogs.- The Molecular Biology of the Vitamin D Receptor.- VDR and RXR Subcellular Trafficking.- Mechanism of Action of 1,25-Dihydroxyvitamin D3 on Intestinal Calcium Absorption and Renal Calcium Transport.- Biological and Molecular Effects of Vitamin D on Bone.- Biological and Molecular Effects of Vitamin D on the Kidney.- Vitamin D and the Parathyroids.- Diversity of Vitamin D Target Genes.- Non-skeletal/Functions of Vitamin D.- Extrarenal Synthesis of 1,25-Dihydroxyvitamin D and Its Health Implications.- Vitamin D and the Innate Immunity.- Vitamin D and Colon Cancer.- Mechanisms of Resistance to Vitamin D Action in Human Cancer Cells.- Vitamin D and the Brain: A Neuropsychiatric Perspective.- Vitamin D Modulation of Adipocyte Function.- Vitamin D Status – Global Analysis.- Determinants of Vitamin D Intake.- 25-Hydroxyvitamin D Assays and Their Clinical Utility.- Health Disparities and Vitamin D.- Vitamin D Deficiency in Canada.- Vitamin D Deficiency and Its Health Consequences in Northern Europe.- Vitamin D Deficiency and Consequences for the Health of People in Mediterranean Countries.- Vitamin D Deficiency in the Middle East and Its Health Consequences.- Vitamin D Deficiency in the Middle East and Its Health Consequences for Adults.- Vitamin D Deficiency and Its Health Consequences in Africa.- Vitamin D Deficiency and Its Health Consequences in India.- Vitamin D Deficiency, Rickets, and Fluorosis in India.- Vitamin D in Asia.- Vitamin D Deficiency and Its HealthConsequences in New Zealand.- Toxicity of Vitamin D.- Health Consequences of Vitamin D Deficiency and Resistance on Musculo Skeletal Health.- Vitamin D Deficiency in Pregnancy and Lactation and Health Consequences.- Vitamin D Deficiency in Children and Its Health Consequences.- Dietary Calcium Deficiency and Rickets.- Vitamin D in Fracture Prevention and Muscle Function and Fall Prevention.- Inherited Defects of Vitamin D Metabolism.- Molecular Defects in the Vitamin D Receptor Associated with Hereditary 1,25-Dihydroxyvitamin D-Resistant Rickets (HVDRR).- Receptor-Independent Vitamin D Resistance in Subhuman and Human Primates.- 25-Hydroxyvitamin D-1?- Hydroxylase: Studies in Mouse Models and Implications for Human Disease.- Sunlight, Vitamin D and Cancer.- The Health Benefits of Solar Irradiance and Vitamin DVitamin D and the Consequences of Their Deprivation.- Vitamin D Status, Solar Radiation and Cancer Prognosis.- The Epidemiology of Vitamin D and Cancer Risk.- Vitamin D Deficiency and the Epidemiology of Prostate Cancer.- Vitamin D for Cancer Prevention and Survival.- The Anti-cancer Effect of Vitamin D: What Do the Randomized Trials Show?.- Sunlight, Skin Cancer, and Vitamin D.- Vitamin D Deficiency and Chronic Disease.- Vitamin D and the Risk of Type 1 Diabetes.- Vitamin D and Multiple Sclerosis.- Vitamin D and Type 2 Diabetes.- Role of Vitamin D for Cardiovascular Health.- Vitamin D, Renin, and Blood Pressure.- Role of Vitamin D and Vitamin D Analogs for Bone Health and Survival in Chronic Kidney Disease.- Role of Vitamin D and Ultraviolet Radiation in Chronic Kidney Disease.- Role of Vitamin D in Rheumatoid Arthritis.- Vitamin D, Respiratory Infections, and Obstructive Airway Diseases.- Clinical Uses of Vitamin D Analogues.- Treatment of ImmunomediatedDiseases by Vitamin D Analogs.- Clinical Utility of 1,25-Dihydroxyvitamin D3 and Its Analogues for the Treatment of Psoriasis.- Affinity Alkylating Vitamin D Analogs as Molecular Probes and Therapeutic Agents.- Anti-inflammatory Activity of Calcitriol That Contributes to Its Therapeutic and Chemopreventive Effects in Prostate Cancer.

Reviews

From the reviews of the second edition:“This comprehensive book covers everything that is currently known about Vitamin D. It discusses topics ranging from the molecular biology of vitamin D and its role in human physiology to its role in health and disease. … an extremely wide audience would find it useful: graduate students, medical students, healthcare professionals, nutritionists, and the lay public. … The book reads consistently and easily from cover to cover, making it accessible to both scientists and nonscientists.” (Heather Huang, Doody’s Review Service, August, 2010)“This valuable and comprehensive monograph is divided in seven parts dealing with introduction and basic biology … . This monograph contains numerous instructive figures, schemes and microphotos which help to understand sophisticated biological and technical processes representing the contemporaneous armament being used in this newly and rapidly development field of diabetology.” (Endocrine Regulations, Fall, 2010)