Table of Contents

I: History & Epidemiology 1: Dengue Viruses: their evolution, history and emergence as a global public health problem 2: Mapping the Epidemiology of Dengue 3: Economic and Disease Burden of Dengue 4: Surveillance for Dengue 5: Dengue Infections in Travelers 6: A review of transmission models of dengue: a quantitative and qualitative analysis of model features II: The Disease 7: Clinical Features of Dengue 8: Neurological Manifestations of Dengue Virus Infection 9: The Southeast Asia Regional Office (WHO) Guidelines for Clinical management of Dengue Hemorrhagic Fever 10: Laboratory Diagnosis of Dengue 11: Dengue Pathogenesis - Host Factors 12: Dengue Pathogenesis – Viral Factors 13: The acquired immune response in dengue virus infection 14: Innate Immune Responses to Dengue Infection 15: Pathology of Dengue Virus Infection 16: Dengue Drug Development III: The virus 17: Taxonomy and Evolutionary Relationships of Flaviviruses 18: Molecular Virology of Dengue Virus 19: The structural biology of dengue virus 20: The Non-Structural Proteins of Dengue Virus IV: Virus-host interaction 21: The Interface between Dengue Virus and the Human Host 22: Dengue Virus-Mosquito Interactions and Molecular Methods of Vector Control 23: Animal Models of Dengue Infection and Disease V: Dengue prevention 24: Dengue vector bionomics: Why Aedes aegypti is such a good vector 25: Surveillance and control of urban dengue vectors 26: Dengue Vector Control - New Approaches 27: Biological control of dengue and Wolbachia-based strategies 28: Dengue Vaccines 29: Dengue Virus Neutralization and Surrogates of Protection

About the Author

Duane J Gubler is Professor and Program director at Duke-NUS Graduate Medical School, Singapore Ooi Eng Eong and Subhash Vasudevan, Duke-NUS Graduate Medical School, Singapore Jeremy Farrar is Professor of Tropical Medicine, Director of the Oxford University Clinical Research Unit in Viet Nam, Ho Chi Minh City, Vietnam