Table of Contents

Viral Entry.- Cellular Entry of the SARS Coronavirus: Implications for Transmission, Pathogenicity and Antiviral Strategies.- The Cell Biology of the SARS Coronavirus Receptor, Angiotensin-Converting Enzyme 2.- Structural Molecular Insights into SARS Coronavirus Cellular Attachment, Entry and Morphogenesis.- Structures Involved in Viral Replication and Gene Expression.- RNA Higher-Order Structures Within the Coronavirus 5? and 3? Untranslated Regions and Their Roles in Viral Replication.- Programmed –1 Ribosomal Frameshifting in SARS Coronavirus.- Viral Proteins.- Expression and Functions of SARS Coronavirus Replicative Proteins.- SARS Coronavirus Replicative Enzymes: Structures and Mechanisms.- Quaternary Structure of the SARS Coronavirus Main Protease.- The Nucleocapsid Protein of the SARS Coronavirus: Structure, Function and Therapeutic Potential.- SARS Coronavirus Accessory Gene Expression and Function.- SARS Accessory Proteins ORF3a and 9b and Their Functional Analysis.- Molecular and Biochemical Characterization of the SARS-CoV Accessory Proteins ORF8a, ORF8b and ORF8ab.- Viral pathogenesis and host immune response.- SARS Coronavirus Pathogenesis and Therapeutic Treatment Design.- Modulation of Host Cell Death by SARS Coronavirus Proteins.- SARS Coronavirus and Lung Fibrosis.- Host Immune Responses to SARS Coronavirus in Humans.- The Use of Retroviral Pseudotypes for the Measurement of Antibody Responses to SARS Coronavirus.- SARS Coronavirus Spike Protein Expression in HL-CZ Human Promonocytic Cells: Monoclonal Antibody and Cellular Transcriptomic Analyses.- Signaling Pathways of SARS-CoV In Vitro and In Vivo.

Reviews

From the reviews:“This volume provides a useful portal for postgraduate students and researchers into selected aspects of SARSr-CoV molecular biology. … this volume would be most useful to postgraduate students entering the field of SARSr-CoV research.” (Stuart Siddell, The Quarterly Review of Biology, Vol. 87, March, 2012)