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Table of Contents

Section I Pharmacological update.- 1 Chemistry and biochemistry of natural estrogens.- 2 Estrogens and prostaglandins.- 3 Plasma concentration of estrogens after application of various estrogen preparations.- 4 Progestogen modification of estrogen-induced endometrial proliferation in climacteric women.- 5 New concepts of estrogenic activity : the role of metabolites in the expression of hormone action.- Section II Clinical update.- 6 Hormonal influences on ?-adrenoreceptors: preliminary results.- 7 ‘Psychotherapeutic effects’ of estrogen substitution during the climacteric period.- 8 Double-blind studies on the effects of natural estrogens on postmenopausal women: a follow-up report.- 9 Considerations concerning the clinical treatment of the principal micturitional disturbances of the postmenopause.- 10 The urethral syndrome — role of estrogens in the therapy.- 11 Relationships of ovary, endometrium and vagina to estrogen therapy in the postmenopause.- 12 Prolactin in postmenopausal endometrial hyperplasia and adenocarcinoma.- 13 The prevention and treatment of endometrial pathology in postmenopausal women receiving exogenous estrogens.- 14 Treatment of patients at risk. Cross-over study between natural estrogens.- 15 Estrogen therapy preparatory to vaginal surgery in advanced menopause.- 16 The correction by estrogens of calcium disorders induced by estrogen-deficient states.- 17 Calcium metabolism in the postmenopause and sex steroid therapy: postmenopausal osteoporosis and sex steroids.- 18 Prevention and treatment of postmenopausal osteoporosis.- 19 The clinical epidemiology of breast and uterine cancer.- 20 Estrogens and endometrial cancer: a pathologist’s perspective.- 21 Steroid-induced changes in the endometrium of postmenopausal women.- 22 Mutagenicityand estrogens.- 23 Estrogens and endometrial cancer. A preliminary report.- 24 Exogenous estrogen therapy in the menopause: influence on mammary cancer risk.- 25 The effects of exogenous estrogen replacement on breast parenchymal patterns.- 26 Replacement therapy of the menopause and breast cancer.- 27 Estrogen and estrogen-progestogen compounds. Is there a risk for the development of endometrial and breast cancer in the perimenopausal woman?.- 28 Role of estrogens and progestogens in the etiology of breast and endometrial neoplasia.- Discussion.