PART 1 BASIC CONCEPTS OF LIFE; 1. The basic molecular themes of life; 2. Cells and viruses; 3. Energy considerations in biochemistry; PART 2 STRUCTURE AND FUNCTION OF PROTEINS AND MEMBRANES; 4. The structure of proteins; 5. Methods in protein investigation; 6. Enzymes; 7. The cell membrane and membrane proteins; 8. Muscle contraction, the cytoskeleton, and molecular motors; PART 3 METABOLISM; 9. Food digestion, absorption, distribution to the tissues and appetite control; 10. Mechanisms of transport, storage and mobilisation of dietary components; 11. Principles of energy release from food; 12. Glycolysis, the citric acid cycle, and the electron transport system; 13. Energy release from fat; 14. The synthesis of fat and related compounds; 15. Synthesis of glucose (gluconeogenesis); 16. Strategies for metabolic control and their applications to carbohydrate and fat metabolism; 17. Why should there be an alternative pathway of glucose oxidation? The pentose phosphate pathway; 18. Raising electrons of water back up the energy scale - photosynthesis; 19. Amino acid metabolism; 20. Nucleotide synthesis and metabolism; PART 4 INFORMATION STORAGE AND UTILISATION; 21. The genome; 22. DNA synthesis, repair and recombination; 23. Gene transcription and control; 24. Protein synthesis and controlled protein breakdown; 25. The RNA world - RNA microgenes and RNA interference; 26. Protein sorting and delivery; 27. Cell signalling; 28. Manipulating DNA and genes; PART 5 MOLECULAR BIOLOGY IN HEALTH AND DISEASE; 29. Special topics: blood clotting, xenobiotic metabolism, reactive oxygen species; 30. The immune system; 31. The cell cycle and its control; 32. Apoptosis; 33. Cancer
Professor William H. Elliott, Emeritus Professor, Department of
Biochemistry, University of Adelaide, Australia
Dr Daphne C. Elliott, formerly Lecturer, Department of
Biochemistry, Flinders University, Adelaide, Australia
Difficult concepts are beautifully and uniquely covered with simple analogies to encourage understanding. The discoveries in biochemistry and molecular biology in the last few years have been very exciting and this book is one of the few texts able to convey this excitement with its unique style. Lynn Rogers, The University of Adelaide, Australia I feel it is one of the best in its class in terms of depth and level for students on multidisciplinary biology and biomedical science courses. I also very much appreciate the increasing emphasis on human examples. Dr Alison Caswell, Leeds Metropolitan University, UK This is a well-written, accessible book, which should appeal to students during their first major encounter with biochemistry and molecular biology. Throughout the book, reference is made to health, disease and treatment, which should make the text more relevant and interesting to undergraduate students, especially those on medically-related courses. Dr Caroline Owen, Kingston University, UK I liked the last edition but it looks as if this will be better. I see an obvious attempt to identify areas which students find difficult and a willingness to take on approaches which help students learn. The book seem to me to be written with its target audience always in mind. I particularly liked the way in which fundamental biological principles are never forgotten. This made my reading of the chapters quite stimulating. Dr John Wright, University of East London, UK
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