Section Editors
Contributors
Foreword
Preface
Acknowledgments
Multidisciplinary Training for Breast Surgical Oncology
The Influence of the News Media and the Internet on Breast Cancer
Patient Care and Research
SECTION 1: ETIOLOGY, ASSESSING RISK, INITIAL EVALUATION, AND
MANAGEMENT, Thomas B. Julian, David Euhus, Irene L. Wapnir
1. Breast Carcinogenesis, Paul J. van Diest, Horst Buerger, Arno
Kuijper, Elsken van der Wall
2. Invasion, Christopher B. Umbricht
3. Metastatis, Alison L. Allan
4. Epidemiology of Breast Cancer, Dezheng Huo, James Dignam
5. Breast Cancer Screening, Haydee Ojeda-Fournier, Christopher E.
Comstock
6. Components of a Breast Care Program, E. Shelley Hwang, Laura J.
Esserman
7. Establishing a Cancer Genetics Service, Deborah J. MacDonald
8. Genetic Predisposition Syndromes, Linda Robinson
9. Quantitative Risk Prediction, David Euhus
10. Chemoprevention in the Clinical Setting, Atilla Soran, Victor
G. Vogel
11. Prophylactic Mastectomy, Judy C. Boughey, Amy C. Degnim
12. History, Physical Examination, and Staging, Christine Laronga,
Sharon Tollin, Kiran Turaga
13. Initial AJCC Staging, C. Denise Ching, Stephen B. Edge, Savitri
Krishnamurthy, S. Eva Singletary
14. Communicating a Breast Cancer Diagnosis, Walter Baile, Laura
Dominici
SECTINON 2: PATHOLOGY OF THE BREAST AND CLINICAL MANAGEMENT,
Savitri Krishnamurthy, Rache M. Simmons
15. Breast Specimen Tissue Processing, Edi Brogi, Violetta
Barbashina
16. Benign Conditions of the Breast, Michael P. Osborne, Susan K.
Boolbol, Juhi Asad
17. High-Risk Lesions: ALH/LCIS/ADH, Chanel E. Smart, Colin M.
Furnival, Sunil R. Lakhani
18. Ductal Carcinoma in Situ, Melvin J. Silverstein, Michael D.
Lagios
19. Paget Disease of the Breast, Nimmi Arora, Rache M. Simmons
20. Invasive Breast Carcinoma, David R. McCready, Naomi A. Miller,
Bruce J. Youngson
21. Male Breast Cancer, Mahmoud El-Tamer, Benjamin Pocock
22. Prognostic and Predictive Factors in Breast Cancer, Celina G.
Kleer, Michael S. Sabel
23. Nonepithelial Neoplasms of the Breast, Tina W.F. Yen, Jennifer
D. Lorek, Zainab Basir
24. Cytology in Breast Care Management, Savitri Krishnamurthy
25. Pathology Post-Neoadjuvant Therapy, W. Fraser Symmans
26. Axillary and Sentinel Lymph Node Evaluation, Roderick R.
Turner, Helen Mabry, Armando E. Giuliano
27. Minimal Residual Cancer, Stephan Braun, Bjorn Naume, Elin
Borgen
SECTION 3: IMAGING, Pat W. Whitworth, Terri-Ann
Gizienski
28. Mammography, Ian Grady, Pat Hansen
29. Stereotactic Breast Biopsy, Rand Stack, Arthur Lerner
30. Anatomy and Ultrasound of the Breast and Atlas of Ultrasound
Findings, Jay K. Harness
31A. Basic Breast Ultrasound, Certification, and Accreditation for
the Surgeon, Howard Snider
31B. Screening Breast Ultrasound, Edgar D. Staren
32. Selection of Ultrasound Machine and Office Setup, Eric A.
Whitacre
33. Image-Guided Percutaneous Breast Biopsy, Pat W. Whitworth
34. Ultrasound Evaluation of the Lymphatic Spread of Breast Cancer,
Bruno D. Fornage
35. Breast Magnetic Resonance Imaging, Elizabeth Morris, Elisa
Port
36. Systemic Staging and the Radiologic Work-Up of Abnormal
Findings, Tanya W. Stephens, Eleni Andreopoulou
SECTION 4: LANDMARK CLINICAL TRIALS IN BREAST SURGICAL
ONCOLOGY, Eleftherios P. Mamounas
37. Statistical Design and Analysis of Phase III Clinical Trials,
Joseph P. Costantino, Stewart Anderson, Greg Yothers
38. Study Conduct, Walter M. Cronin
39. Protocol Components and Production, Alice Matura, Aurora
Madrigal
40. Tissue Acquisition and Banking for Breast Cancer, Soonmyung
Paik
41. Funding for Clinical Trials, Edward L. Trimble, Andrea
Denicoff, Jeffrey Abrams
42. The NSABP Experience, Eleftherios P. Mamounas, D. Lawrence
Wickerham, Bernard Fisher, Charles E. Geyer, Thomas B. Julian,
Norman Walmark
43. The Milan Cancer Institute's Landmark Clinical Trials, Umberto
Veronesi, Stefano Zurrida
44. The ACOSOG Experience, Judy C. Boughey, Kelly K. Hunt
45. The EORTC Experience: From DCIS to Locally Advanced Breast
Cancer, Harry Bartelink, Philip Meijnen, Marieke Straver, Emiel
Rutgers
46. The UK Experience, Jayant S. Vaidya
47. The Austrian Breast and Colorectal Cancer Study Group
Experience, Sebastian F. Schoppmann, Karl Thomanek, Michael Gnant,
Raimund Jakesz
48. The German Experience: Primary Systemic Therapy with Cytotoxic
Agents, Michael Untch, Gunter von Minckwitz
49. The Eastern Cooperative Oncology Group (ECOG) Experience,
Lawrence J. Solin
50. The Cancer and Leukemia Group B Trials, Amanda J. Wheeler,
Barbara L. Smith, Kevin Hughes
51. The RTOG Experience, Beryl McCormick, Julia White
SECTION 5: OPERATIVE MANAGEMENT, Anthony Lucci, Tari
King
52. Paravertebral Block as an Anesthetic Technique in Patients
Undergoing Breast Cancer Surgery, Farzin Goravanchi, Ronald
Parris
53. Excisional Breast Biopsy, Leslie Montgomery
54. Tissue Marking and Processing, Amanda L. Kong, Alexandra Shaye
Brown
55. Needle Localization and Radioguided Occult Lesion Localization
Techniques, Simonetta Monti, Julia Rodriquez-Fernandez, Helio
Rubens De Oliveira Filho
56. Mammographic and Intraoperative Ultrasound Guidance, Richard E.
Fine
57. Central Duct Exploration for Nipple Discharge, Lisa M.
Sclafani
58. Endoscopy for Nipple Discharge, Julian Kim
59. Intraductal Therapy, Robert J. Goulet, Jr., Theodore N.
Tsangaris, Susan M. Love
60. Cryoablation of Fibroadenomas, Pat W. Whitworth, Jaime
Lewis
61. Breast-Conserving Surgery, Mary Morrogh, Vittorio Zanini, Lea
Regolo, Bettina Ballardini, Lisa Wiechmann, Virgilio Sacchini
62. Sentinel Lymph Node Biopsy, Jennifer R. Garreau, Armando E.
Giuliano
63. Axillary Lymph Node Dissection, Heather B. Neuman, Kimberly J.
Van Zee
64. Modified Radical Mastectomy and Techniques for Avoiding Skin
Necrosis, Rashni Rao, A. Marilyn Leitch
65. The Concept of Prophylactic Mastectomy, Isabelle Bedrosian
66. Skin-Sparing Mastectomy, Judy C. Boughey, Kari M.
Rosenkranz
67. Nipple- and Areola-Sparing Mastectomy, Meredith Kato, Rache M.
Simmons
68. Radical and Extended Radical Mastectomy, Regina M. Fearmonti,
Elisabeth K. Beahm
69. Management of Local Recurrence after Mastectomy, Anees B.
Chagpar
70. Surgery for Gynecomastia, Sarah McLaughlin, Hiram S. Cody
71. Central Venous Access in Breast Oncology Patients, April
Spencer, Ervin B. Brown
72. Surgery in Patients with Stage IV Metastatic Breast Cancer,
Jane E. Mendez, S. Eva Singletary, Gildy V. Babiera
SECTION 6: PLASTIC AND BREAST RECONSTRUCTION, Steven J.
Kronowitz
73. The Epidemiology of Breast Reconstruction in North America, Amy
K. Alderman, Rachel Streu, Edwin G. Wilkins
74. Oncologic Considerations for Breast Reconstruction, Grant W.
Carlson
75. Considerations and Strategies for the Timing of Breast
Reconstruction, Steven J. Kronowitz
76. Partial Breast Reconstruction Using Local Tissue, Albert
Losken
77. Immediate Repair of Partial Mastectomy Defects Using Perforator
Flaps, Moustapha Hamdi, Filip Stillaert
78. Correction of Partial Breast Deformities with the Lipomodeling
Technique, Emmanuel Delay
79. Implant-Based Reconstruction, Peter Cordeiro, Colleen
McCarthy
80. Breast Reconstruction with the Autogenous Latissimus Flap,
Barbara Persons, Beth Collins, Christoph Papp, John McCraw
81. Total Breast Reconstruction Using Autologous Tissue: TRAM,
DIEP, and SIEA Flaps, Maurice Y. Nahabedian, Ketan Patel
SECTION 7: SYSTEMIC THERAPY OF BREAST CANCER, Lisa Carey,
David W. Ollila
82. General NCCN Guidelines, P.K. Morrow, Richard Theriault
83. Selection of Patients for Therapy, William Irvin, Jr., Keith
Amos
84. Neoadjuvant Endocrine Therapy, E. Jane Macaskill, J. Michael
Dixon
85. Neoadjuvant Chemotherapy, Funda Meric-Bernstam
86. Endocrine Therapy, Prudence A. Francis
87. Adjuvant Chemotherapy, Sara M. Tolaney, Ian E. Krop
88. Biologic Therapy, Janet K. Horton, E. Claire Dees, Nancy
Klauber-DeMore
89. Pregnancy and Breast Cancer, David W. Ollila, Susan
Mckenney
90. Inflammatory Breast Cancer, Viviana Negron Gonzalez, Julia L.
Oh, Massimo Cristofanilli, Gildy V. Babiera
91. Breast Cancer Vaccines, Elizabeth A. Mittendorf, Brian J.
Czerniecki, George E. Peoples
92. Metastatic Breast Cancer, Hope S. Rugo
SECTION 8: RADIATION, Bruce G. Haffty
93. Conceptual Basis and Principles of Radiation Oncology, Bruce G.
Haffy, Venkat Narra, Ning J. Yue
94. Whole-Breast Radiation Following Breast-Conserving Therapy for
Noninvasive and Invasive Cancers, Meena S. Moran
95. Accelerated Partial Breast Irradiation, Sharad Goyal, Victor
Zannis
96. Postmastectomy Radiation Therapy, Atif J. Khan, Bruce G.
Haffty
97. Radiation Therapy in Metastatic Disease, Kathleen C. Horst
SECTION 9: FOLLOW-UP AND COMPLICATIONS FOLLOWING DIAGNOSIS AND
THERAPY, Tara Breslin, Mehra Golshan
98. Guidelines for Follow-Up, Alicia Growney, Jennifer J.
Griggs
99. Tumor Registry, Luke M. Funk, Caprice C. Greenberg
100. Psychosocial, Michelle B. Riba, Prachi Agarwa la
101. Fertility, Sexuality, and Menopausal Symptom Management,
Kathryn J. Ruddy, Ann H. Partridge
102. Disparities in Breast Cancer, Nicholas Osborne, Lisa
Newman
103. Surgical Complications and Management, Kandice E. Kilbride
104. Lymphedema, Steve Norton
105. Diet and Exercise in Breast Cancer Survivorship, Jennifer
Ligibel
Index
Henry M. Kuerer, MD, PhD, FACS Professor, Department of Surgical Oncology Director, Breast Surgical Oncology Training Program University of Texas MD Anderson Cancer Center Houston, TX
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