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Veterinary Hematology and Clinical Chemistry
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Table of Contents

Contributors ix

Preface x

Preface to the First Edition xii

Section I General Principles of Laboratory Testing and Diagnosis 1

1 Laboratory Technology for Veterinary Medicine 3
Glade Weiser

2 Sample Collection Processing and Analysis of Laboratory Service Options 34
Glade Weiser

3 Perspectives in Laboratory Data Interpretation and Disease Diagnosis 40
Glade Weiser and Robin W. Allison

4 Immunodiagnostics: Current Use and Future Trends in Veterinary Medicine 51
Wayne A. Jensen

Section II Hematology of Common Domestic Species 59

5 Erythrocyte Morphology 61
Mary Anna Thrall

6 Classification of and Diagnostic Approach to Anemia 75
Mary Anna Thrall

7 Nonregenerative Anemia 81
Mary Anna Thrall

8 Regenerative Anemia 87
Mary Anna Thrall

9 Classification of and Diagnostic Approach to Polycythemia 114
Mary Anna Thrall

10 Introduction to Leukocytes and the Leukogram 118
Glade Weiser

11 Neutrophil Production Trafficking and Kinetics 123
Glade Weiser

12 Interpretation of Leukocyte Responses in Disease 127
Glade Weiser

13 Molecular Diagnostics of Hematologic Malignancies 140
Anne Avery

14 Laboratory Evaluation of Bone Marrow 150
Mary Anna Thrall and Glade Weiser

15 Lymphoproliferative Disorders and Myeloid Neoplasms 166
Mary Anna Thrall

16 Diagnosis of Disorders of Hemostasis 185
Dale C. Baker

17 Principles of Blood Transfusion and Crossmatching 205
Diane Brown and Linda M. Vap

Section III Hematology of Common Nondomestic Mammals Birds Reptiles Fish and Amphibians 223

18 Mammalian Hematology: Laboratory Animals and Miscellaneous Species 225
Terry W. Campbell

19 Hematology of Birds 238
Terry W. Campbell

20 Hematology of Reptiles 277
Terry W. Campbell

21 Hematology of Fish 298
Terry W. Campbell

22 Hematology of Amphibians 313
Terry W. Campbell

Section IV Clinical Chemistry of Common Domestic Species 321

23 Laboratory Evaluation and Interpretation of the Urinary System 323
Donald Meuten

24 Laboratory Evaluation of Electrolytes 378
Andrea A. Bohn

25 Laboratory Evaluation of Acid-Base Disorders 393
Glade Weiser

26 Laboratory Evaluation of the Liver 401
Robin W. Allison

27 Laboratory Evaluation of the Pancreas and Glucose Metabolism 425
Robin W. Allison

28 Laboratory Evaluation of Digestion and Intestinal Absorption 441
Dawn Seddon

29 Laboratory Evaluation of Plasma and Serum Proteins 460
Robin W. Allison

30 Laboratory Detection of Muscle Injury 476
Robin W. Allison

31 Laboratory Evaluation of Lipids 480
M. Judith Radin

32 Laboratory Evaluation of the Thyroid Adrenal and Pituitary Glands 497
Donald Meuten

33 Parathyroid Glands and Calcium and Phosphorus Metabolic Pathology 545
Donald Meuten

Section V Clinical Chemistry of Common Nondomestic Mammals Birds Reptiles Fish and Amphibians 569

34 Chemical Chemistry of Mammals: Laboratory Animals and Miscellaneous Species 571
Terry W. Campbell

35 Clinical Chemistry of Birds 582
Terry W. Campbell

36 Clinical Chemistry of Reptiles 599
Terry W. Campbell

37 Clinical Chemistry of Fish and Amphibians 607
Terry W. Campbell

Section VI Clinical Case Presentations 615

This section includes 74 cases with clinicopathologic data accompanied by an interpretive discussion and diagnostic summary.

Index 750

About the Author

Mary Anna Thrall, DVM, MS, DACVP, is a Professor and Section Chief, Department of Pathobiology at Ross University School of Veterinary Medicine in Basseterre, St. Kitts, West Indies. Glade Weiser, DVM, DACVP, is a Professor, Special Appointment, in the Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine & Biomedical Sciences at Colorado State University in Fort Collins, Colorado. Robin W. Allison, DVM, PhD, Dipl ACVP, is an Associate Professor in the Department of Veterinary Pathobiology, Center for Veterinary Health Sciences at Oklahoma State University in Stillwater, Oklahoma. Terry W. Campbell, DVM, PhD is a Professor in the Department of Clinical Sciences at Colorado State University in Fort Collins, Colorado.

Reviews

It will also prove to be of benefit for clinicalpathology residents and specialists who deal with nondomestic andexotic species. (Journal of The American VeterinaryMedical Association, 15 March 2013) I found the self-study part really useful ... A greatinvestment to help you decipher the mysteries of the labreports. (Tomorrow's vets, 1 September2013) This book cannot be highly recommended enough to the vetstudent, and I believe it is just as indispensable for theveterinary surgeon in practice no mean feat for atextbook. (Veterinary Practice News, 1September 2013) In summary, this is a comprehensive text with a strongpractical and clinical focus and. It s clearly written andsupplemented by generous numbers of quality images ... This bookhas a small animal bias and as such will be of greatest interest tosmall animal clinicians, but will also be valuable to cliniciansseeing mixed practice, or delving into providing small mammal orexotic pet clinical pathology. (AustralianVeterinary Journal, 9 September 2013) The second edition certainly fulfils its stated objectiveand is a valuable resource for its targeted audience. It willalso prove be benefit for clinical pathology residents andspecialists who deal with nondomestic and exoticspecies. (Journal of the American VeterinaryMedical Association, 15 March 2013) Overall, I think this book is well written and beautifullypresented. It appears to bridge the gap between undergraduateand postgraduate readers and covers all the species likely to beencountered in mixed veterinary practice. ( Veterinary Record, 16 March 2013) "Mary Anna Thrall, et.al.'s VETERINARY HEMATOLOGY AND CLINICALCHEMISTRY, 2ND EDITION (9780813810270, $99.99) offers a key tounderstanding veterinary laboratory diagnostic techniques andinterpretation and covers hematology and chemistry for a range ofspecies to include fish, amphibians and birds. This second editionincludes many revisions and additions, from new chapters onmolecular diagnostics of hematologic malignancies to updates inadvancements on diagnostic technology and revisions to datainterpretation. Both elementary basics and advanced laboratorytechniques are covered in a guide that offers over seventy casestudies to help readers understanding the entire laboratoryprocess, making for a top recommendation for veterinary referencecollections." (Midwest Book Reviews, 1 December2012)"It's a powerful reference packed with practical applications andshould be considered a 'must' for any veterinary referencelibrary." ( Midwest Book Reviews, 1 November 2012)

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