RICKI LEWIS is a Ph.D. geneticist, journalist, professor and genetic counselor. The author of one of the most widely used college textbooks in the field (Human Genetics: Concepts and Applications, now in its 10th edition), she has also written hundreds of popular pieces on science and other topics for trade and specialized magazines, including Nature, Discover, and The Scientist.
In this impressive, meticulously researched study of the exciting
new developments in gene therapy, geneticist and journalist Lewis
(Human Genetics) looks closely at the history of setbacks plaguing
the treatment of rare genetic diseases as well as recent
breakthroughs...Yet with each success, as Lewis recounts in this
rigorous, energetic work, possibilities in treating HIV infection
and dozens of other diseases might be around the next corner.
"Publisher's Weekly (starred review)" A fascinating account of
groundbreaking science and the people who make it possible.
"Kirkus" Ricki Lewis gives us the inspiring story of gene therapy
as told through Corey's eyes--literally. Her book delves into the
challenges modern medicine faces--both in its bitter
disappointments and great successes--but it goes much deeper than
that. With empathy and grace, Lewis shows us the unimaginable
strength of parents with sick children and the untiring devotion of
the physicians who work to find the forever fix' to save them. But
best of all Lewis gives us a story of profound hope. "Molly
Caldwell Crosby, author of The American Plague: The Untold Story of
Yellow Fever, the Epidemic that Shaped Our History and Asleep: The
Forgotten Epidemic that Remains One of Medicine's Greatest
Mysteries" "The Forever Fix" is a wonderful story told by one of
our most gifted science and medical writers. In the tradition of
Siddhartha Mukherjee's "The Emperor of All Maladies," Ricki Lewis
explains complex biological processes in extremely understandable
ways, ultimately providing crucial insights into the modeling of
disease and illustrating how gene therapy can treat and even
potentially cure the most challenging of our health conditions.
Dennis A. Steindler, Ph.D., former Executive Director of the
McKnight Brain Institute, University of Florida Ricki Lewis has
written a remarkable book that vividly captures the breathtaking
highs and devastating lows of gene therapy over the past decade
while giving ample voice to all sides -- the brave patient
volunteers, their parents and physicians. "The Forever Fix" is
required reading as we dare to dream of curing a host of genetic
diseases. "Kevin Davies, Founding editor of Nature Genetics; author
of The $1,000 Genome and Cracking the Genome" In 'The Forever Fix,
' Ms. Lewis chronicles gene therapy's climb toward the Peak of
Inflated Expectations over the course of the 1990s. A geneticist
and the author of a widely used textbook, she demonstrates a
mastery of the history. "The Wall Street Journal" An engaging and
accessible look at gene therapy. "Times Union" Medical writer Ricki
Lewis interweaves science, the history of medical trial and error,
and human stories from the death in 1999 of teenager Jesse
Gelsinger, from a reaction to gene therapy intended to combat his
liver disease, to radical successes in some children with adenosine
deaminase deficiency. "Nature" Lewis adeptly traverses the highs
and lows of gene therapy and explores its past, present, and future
through the tales of those who've tested its validity. "The
Scientist""
"In this impressive, meticulously researched study of the exciting
new developments in gene therapy, geneticist and journalist Lewis
(Human Genetics) looks closely at the history of setbacks plaguing
the treatment of rare genetic diseases as well as recent
breakthroughs...Yet with each success, as Lewis recounts in this
rigorous, energetic work, possibilities in treating HIV infection
and dozens of other diseases might be around the next
corner."--"Publisher's Weekly" (starred review) "A fascinating
account of groundbreaking science and the people who make it
possible." --"Kirkus""Ricki Lewis gives us the inspiring story of
gene therapy as told through Corey's eyes--literally. Her book
delves into the challenges modern medicine faces--both in its
bitter disappointments and great successes--but it goes much deeper
than that. With empathy and grace, Lewis shows us the unimaginable
strength of parents with sick children and the untiring devotion of
the physicians who work to find 'the forever fix' to save them. But
best of all Lewis gives us a story of profound hope." --Molly
Caldwell Crosby, author of "The American Plague: The Untold Story
of Yellow Fever, the Epidemic that Shaped Our History" and "Asleep:
The Forgotten Epidemic that Remains One of Medicine's Greatest
Mysteries" ""The Forever Fix" is a wonderful story told by one of
our most gifted science and medical writers. In the tradition of
Siddhartha Mukherjee's "The Emperor of All Maladies," Ricki Lewis
explains complex biological processes in extremely understandable
ways, ultimately providing crucial insights into the modeling of
disease and illustrating how gene therapy can treat and even
potentially cure the most challenging of our health conditions." -
Dennis A. Steindler, Ph.D., former Executive Director of the
McKnight Brain Institute, University of Florida "Ricki Lewis has
written a remarkable book that vividly captures the breathtaking
highs and devastating lows of gene therapy over the past decade
while giving ample voice to all sides -- the brave patient
volunteers, their parents and physicians. "The Forever Fix" is
required reading as we dare to dream of curing a host of genetic
diseases." --Kevin Davies, Founding editor of "Nature Genetics";
author of "The $1,000 Genome" and "Cracking the Genome""In 'The
Forever Fix, ' Ms. Lewis chronicles gene therapy's climb toward the
Peak of Inflated Expectations over the course of the 1990s. A
geneticist and the author of a widely used textbook, she
demonstrates a mastery of the history." "-- The Wall Street
Journal"
"An engaging and accessible look at gene therapy." --"Times
Union
""Medical writer Ricki Lewis interweaves science, the history of
medical trial and error, and human stories ... from the death in
1999 of teenager Jesse Gelsinger, from a reaction to gene therapy
intended to combat his liver disease, to radical successes in some
children with adenosine deaminase deficiency." --"Nature
""Lewis adeptly traverses the highs and lows of gene therapy and
explores its past, present, and future through the tales of those
who've tested its validity." -"The Scientist"
"Ricki Lewis gives us the inspiring story of gene therapy as told
through Corey's eyes--literally. Her book delves into the
challenges modern medicine faces--both in its bitter
disappointments and great successes--but it goes much deeper than
that. With empathy and grace, Lewis shows us the unimaginable
strength of parents with sick children and the untiring devotion of
the physicians who work to find 'the forever fix' to save them. But
best of all Lewis gives us a story of profound hope." --Molly
Caldwell Crosby, author of "The American Plague: The Untold Story
of Yellow Fever, the Epidemic that Shaped Our History" and "Asleep:
The Forgotten Epidemic that Remains One of Medicine's Greatest
Mysteries"
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