Table of Contents

1 Pleural disease: historic perspective
PART ONE: Basic Science
2 Anatomy of the pleura
3 Mesothelial cells
4 Normal physiological fluid and cellular contents
5 Physiology: fluid and solute exchange in normal physiological states
6 Physiology: changes with pleural effusion and pneumothorax
7 Pleural inflammation and infection
8 Immunology
9 Pleural fibrosis
10 Pleural reaction to mineral dusts
11 Genetic alterations in mesothelioma pathogenesis
12 Proteomics in pleural disease
13 Pleural pharmacokinetics
14 Experimental models: pleural disease other than mesothelioma
15 Experimental models: mesothelioma
PART TWO: Clinical Science
16 Approach to patients with pleural diseases
17 Pleural fluid analysis
18 Pleural manometry
19 Radiology: diagnostic
20 Radiology: interventional
21 Radiology: pleural ultrasound
22 Pathology: histology
23 Pathology: cytology
EFFUSIONS
24 Effusions from cardiac diseases
25 Effusions from malignancy
26 Effusions from infections: parapneumonic effusions and empyema
27 Effusions from infections: tuberculosis
28 Effusions from infections: atypical infections
29 Effusions from lymphatic disruptions
30 Effusions from vascular causes
31 Effusions in immunocompromised hosts
32 Effusions from connective tissue diseases
33 Effusions caused by drugs
34 Effusions after surgery
35 Hepatic hydrothorax
36 Effusions caused by gastrointestinal disease
37 Effusions of obstetric or gynecological origin
38 Benign fibrous tumor of the pleura
39 Undiagnosed pleural effusions
ASBESTOS-RELATED DISEASES
40 Asbestos-related pleural diseases
41 Malignant mesothelioma
PNEUMOTHORAX
42 Spontaneous pneumothorax
43 Non-spontaneous pneumothorax
PEDIATRIC CONSIDERATIONS
44 Pediatric pleural diseases
INTERVENTION PROCEDURES
45 Drainage techniques
46 Pleurodesis
47 Medical thoracoscopy
48 Surgery for pleural diseases
49 Gene therapy in pleural diseases
CONCLUSION
50 Future directions

About the Author

Richard W Light MD FCCP Professor of Medicine, Vanderbilt University, Nashville, TN, USA YC Gary Lee MBChB PhD FRACP FCCP Consultant Chest Physician and Senior Lecturer, Oxford Centre for Respiratory Medicine and University of Oxford, Oxford, UK; Research Team Leader, Centre for Respiratory Research, University College London, London, UK; and Associate Professor (Honorary), University of Western Australia, Perth, Australia

Reviews

"This is a clearly presented multi-author textbook of pleural diseases ... This book offers an encyclopaedic coverage of pleural disease, and should find a place in every respiratory department."

British Journal of Hospital Medicine