Table of Contents

Introduction. In Vitro Evaluations of Human Placental Functions and Toxic Responses. Pharmacokinetic Aspects of In Vitro Teratogenicity Studies: Comparison to In Vivo. Application of Cell-Cell Communication Assays to Problems of Developmental Toxicology. Cell Migration and Contractility. Analysis of Cell Proliferation in Developing Orofacial Tissue. Membrane Lipid Metabolism and Development of the Palate. In Vitro Assays of Cell Adhesion: Application to Teratogenicity Testing. In Vitro Approaches to the Study of Embryonic Cell Death in Developmental Toxicity. The Regulation of Genes Encoding Extracellular Matrix Proteins: In Vitro Studies and Relationships to Teratogenic Mechanisms. In Vitro Assays in Developmental Toxicology: Their Potential Application in Risk Assessment.