Table of Contents

I. Evaluation and Treatment of Benign Breast Disease Infectious Disorders of the Breast Congenital and Acquired Disorders of Breast Development and Growth Etiology and Management of Breast Pain Nipple Discharge Gynecomastia Management of Benign Breast Lesions II. Epidemiology and Genetics of Breast Cancer 1. Epidemiology of Breast Cancer 2. Breast Cancer Genetic Syndromes 3. Genetic Counseling and Screening III. Primary Prevention of Breast Cancer 1. Quantitative Risk Assessment 2. Ductal Lavage in Risk Reduction 3. Breast Cancer Chemoprevention 4. Surgical Risk Reduction: Prophylactic Mastectomy and Prophylactic Bilateral 5. Salpingo-oophorectomy 6. Prophylactic Mastectomy Reconstructive Options IV. Staging of Breast Cancer AJCC Staging System Prognostic Factors in Breast Cancer Histologic Grading V. Screening and Diagnosis of Breast Cancer Breast Self-Examination Screening and Detection Standard versus Digital Mammograph Breast Ultrasound Magnetic Resonance Imaging Ductoscopy Sterotactic Breast Biopsy Indications and Techniques for Excisional Biopsy VI. Management of In Situ Carcinoma 1. Clinical Management of Lobular Carcinoma In Situ 2. Ductal Carcinoma In Situ: Pathology 3. Ductal Carcinoma In Situ: The Importance of Margins 4. Lymphatic Mapping for Ductal Carcinoma In Situ 5. Role of Adjuvant Endocrine Therapy in Ductal Carcinoma In Situ of the Breast 6. Role of Radiation in the Treatment of Ductal Carcinoma In Situ of the Breast 7. Role of Mastectomy and Breast Reconstruction VII. Locoregional Management of Stage I and II Breast Cancer 1. Breast Conservation Therapy: Selection Criteria 2. Breast Conservation Therapy: Margin Assessment 3. Axillary Staging 4. Sentinel Lymph Node Biopsy in Breast Cancer: The MDACC Approach 5. Role of Radiation Therapy 6. Management of Local Recurrance 7. Reconstructive Strategies in Breast Construction Therapy 8. Implant Reconstruction 9. Autogenous Reconstruction 10. Breast Reconstruction and Radiation Therapy 11. Postmastectomy Radiotherapy in Operable Breast Cancer VIII. Systemic Management of Stage I and II Breast Cancer 1. Adjuvant Hormonal Therapy in Premenopausal Woman 2. Adjuvant Hormonal Therapy in Postmenopausal Women 3. Adjuvant Chemotherapy 4. Preoperative Systemic Therapy for Breast Cancer 5. Occult Micrometastasis in Bone Marrow and Blood IX. Management of Advanced Local and Regional Disease 1. Locally Advanced Breast Cancer 2. Feasibility of Breast Conservation Surgery 3. Sentinel Node Mapping after Chemotherapy 4. Chest Wall Reconstruction for Malignancies of the Breast 5. Role of Radiation Therapy 6. Management of Supraclavicular Nodal Metastases 7. Positron Emission Tomography X. Management of Systemic Disease 1. Chemotherapy Guidelines for Metastatic Breast Cancer 2. Endocrine Therapy for Metastatic Breast Cancer 3. Management of Osseous Metastases and Impending Pathological Fractures 4. Management of Chest, Pulmonary, Pleural and Pericardial Metastases 5. Management of Central Nervous System Metastases in Breast Cancer 6. Neurologic Complications 7. Surgical Management of Liver Metastases XI. Special Presentations of Breast Cancer 1. Bilateral Breast Cancer 2. Cancer of the Male Breast 3. Management of Breast Cancer in Pregnancy 4. The Unknown Primary Presenting with Axillary Lymphadenopathy 5. Management of Breast Cancer in the Augmented Breast 6. Management of Local Recurrence in the Reconstructed Breast 7. Lymphoma of the Breast 8. Sarcoma of the Breast 9. Paget's Disease 10. Cystosarcoma 11. Tubular, Mucinous, and Medullary Carcinoma 12. Breast Cancer Worldwide 13. Breast Cancer in Older Women XII. Follow-up Care and Rehabilitation 1. Follow-up Guidelines 2. Hormone Replacement Therapy and the Risk of Breast Cancer 3. Psychosocial Consequences of Breast Cancer 4. Psychosocial Interventions 5. Lymphedema 6. Patient's Perspective 7. Reproductive Issues 8. Managing Menopausal Problems 9. End of Life Considerations 10. Medicolegal Aspects of Breast Cancer Evaluation and Treatment XIII. Future Directions 1. Targeted Therapies 2. Minimal Invasive Surgical Techniques 3. Molecular Profiling of Breast Cancer 4. Optical Technologies for Noninvasive Functional and Molecular Imaging