Table of Contents

1.Biochemistry and Medicine 2.Water & PH 3.Amino Acids and Peptides 4.Proteins: Determination of Primary Structure 5.Proteins: Higher Orders of Structure 6.Proteins: Myoglobin and Hemoglobin 7.Enzymes: Mechanisms of Action 8.Enzymes: Kinetics 9.Enzymes: Regulation of Activities 10.Bioenergetics: The Role of ATP 11.Biologic Oxidation 12.The Respiratory Chain & Oxidative Phosphorylation 13.Carbohydrates of Physiologic Significance 14.lipids of Physiologic Significance 15.Overview of Metabolism 16.The Citric acid Cycle: The Catabolism of Acetyl-CoA 17.Glycolysis and Oxidation of Pyruvate 18.Metabolism of Glycogen 19.Gluconeogenesis and Control of the Blood Glucose 20.The Pentose Phosphate Pathway & other Pathways of Hexose Metabolism 21.Biosynthesis of Fatty Acids 22.Oxidation of Fatty Acids: Ketogenesis 23.Metabolism of Unsaturated Fatty Acids & Eicosanoids 24.Metabolism of Acyglycerols and Sphingolipids 25.Lipid Transport And Storage 26.Cholesterol Synthesis, Transport and Excretion 27.Integration of Metabolism- the Provision of Metabolic Fuels 28.Biosynthesis of Nutritionally Nonessential Amino Acids 29.Catabolism of Proteins & of Amino Acid Nitrogen 30.Catabolism of the Carbon Skeletons of Amino Acids 31.Conversion of Amino Acids 32.Porphyrins & Bile Pigments 33.Nucleotides 34.Metabolism of Purine & Pyrimidine Nucleotides 35.Nucleic Acid Structure and Function 36.DNA Organization, Replication and Repair 37.RNA Synthesis, Processing and Modifications 38.Protein Synthesis and Genetic Code 39.Regulation of Gene Expression 40.Molecular Genetics, Recombinant DNE and Genomic Technology 41.Membranes: Structure and Function 42.The Diversity of Endocrine System 43.Hormone Action and Signal Transduction 44.Nutrition, Digestion and Absorption 45.Vitamins and Minerals 46.Intracellular Traffic and Sorting of Proteins 47.Glycoprotein 48.The Extracellular Matrix 49.Muscle and the Cytoskeleton 50.Plasma Proteins and Immunoglobulins 51.Homeostasis and Thrombosis 52.The Red and White Blood Cells 53.Metabolism of Xenobiotics 54.The Human Genome Project

About the Author

McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide Robert K. Murray, MD, PhD

Professor (Emeritus) of Biochemistry

University of Toronto

Toronto, Ontario

Daryl K. Granner, MD

Joe C. Davis Professor of Biomedical Science

Director, Vanderbilt Diabetes Center

Professor of Molecular Physiology and Biophysics
and of Medicine

Vanderbilt University

Nashville, Tennessee

Peter A. Mayes, PhD, DSc

Emeritus Professor of Veterinary Biochemistry

Royal Veterinary College

University of London

London

Victor W. Rodwell, PhD

Professor of Biochemistry

Purdue University

West Lafayette, Indiana