The second edition of Clark and Pazdernik's Molecular Biology examines the basic concepts of molecular biology while incorporating primary literature from today's leading researchers.
Unit 1: Basic Chemical and Biological Principles1. Cells and Organisms 2. Basic Genetics 3. DNA, RNA, and Protein 4. Genes, Genomes, and DNA 5. Manipulation of Nucleic Acids Unit 2: The Genome6. Polymerase Chain Reaction 7. Cloning Genes for Analysis 8. DNA Sequencing 9. Genomics & Systems Biology Unit 3: The Central Dogma of Molecular Biology10. Cell Division and DNA Replication 11. Transcription of Genes 12. Processing of RNA 13. Protein Synthesis 14. Protein Structure & Function 15. Proteomics: Global Analysis of Proteins Unit 4: Regulating Gene Expression16. Regulation of Transcription in Prokaryotes 17. Regulation of Transcription in Eukaryotes 18. Regulation at RNA Level 19. Analysis of Gene Expression (Transcriptome) Unit 5: Subcellular Life Forms20. Plasmids 21. Viruses 22. Mobile DNA Unit 6: Changing the DNA Blueprint23. Mutations and Repair 24. Recombination 25. Bacterial Genetics 26. Molecular Evolution
Dr. Clark has taught courses in Molecular Biology and Bacterial Physiology and Biochemistry at Southern Illinois University since 1981. Research into the Regulation of Alcohol Fermentation in E. coli has been funded by the U.S. Department of Energy, Office of Basic Energy Sciences from 1982 till present. Supervised 11 master's and 7 PhD students Published approximately 70 articles in scientific journals Previously published work includes "Molecular Biology Made Simple and Fun" coauthored with Lonnie Russell. (Cache River Press, Vienna, IL, First edition, 1997 and Second edition, 2000)
"This molecular biology textbook from Clark and Pazdernik is geared toward upper-level undergraduate and beginning graduate students. The book is written with a preference for breadth over depth, beginning with several chapters to cover the basics for students with a non-molecular background in biology and continuing on in survey fashion to the topics of genomics research, RNA and protein function, gene expression, subcellular life-forms, and DNA alteration."--Reference & Research Book News, October 2013 "This book reflects the massive surge in our understanding of the molecular foundations of genetics. In order to understand where these technological advances are heading, there needs to be a basic understanding of how living organisms function at a molecular level. Molecular Biology, 2e, effectively introduces basic concepts followed by more specific applications as the text evolves."--ANTICANCER RESEARCH 33: 745-746 (2013), February 2013 "This comprehensive text gives students and researchers a sound and practical knowledge of molecular biology. Consisting of 28 lucidly written chapters, this book presents basic concepts, recent updates, methodological principles and applications in this central biology discipline. The authors have adopted an interesting pedagogic approach to ensure smooth delivery of the presented information. This involved the use of nicely-designed meaningful illustrations, highlighting key concepts in each chapter, and raising review and conceptual questions. There is also a novel feature of 'Focus on Relevant Research' sections relating pertinent research articles to key concepts in the text. These sections illustrate how the development of frontier research in molecular biology is based upon the proper understanding of its prime concepts. This second edition of the text is accompanied by an online study guide, which contains useful material including review questions, and references to relevant articles. I would highly recommend this informative, well-presented book to students and researchers seeking sound and practical updated knowledge in molecular biology."--Science Progress
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