Table of Contents

PART A; Pharmacodynamics and pharmacokinetics; 1. Drugs and the medicinal chemist; 2. The why and the wherefore - drug targets; 3. Proteins as drug targets; 4. Proteins as drug targets - enzymes; 5. Proteins as drug targets - receptors; 6. Proteins as drug targets - receptor structure and signal transduction; 7. Nucleic acids as drug targets; 8. Pharmacokinetics and related topics; PART B; Drug discovery, design and development; 9. Drug discovery - finding a lead; 10. Drug design - pharmacodynamics; 11. Drug design - pharmacokinetics; 12. Drug development; PART C; Tools of the trade; 13. Quantitative structure-activity relationships (QSAR); 14. Combinatorial synthesis; 15. Computers in medicinal chemistry; PART D; Topics in medicinal chemistry; 16. Antibacterial agents; 17. Antiviral drugs; 18. Anticancer agents; 19. The peripheral nervous system - cholinergics, anticholinergics, and anticholinesterases; 20. The adrenergic nervous system; 21. The opium analgesics; 22. Anti-ulcer agents

Reviews

...an excellent book in the always changing field of medicinal chemistry.--Doody's Book Review