Table of Contents

Section 1: Introduction
1.1: Geoff Hanks, Nathan I. Cherny, Stein Kaasa, Russ Portenoy, Nicholas Christakis & Marie Fallon: Introduction
Section 2: The worldwide status of palliative care
2.1: David Clark: International progress in creating palliative medicine as a specialized discipline
2.2: Perry Fine & Stephen Connor: Lessons learned from hospice in the United States of America
2.3: Robert Twycross & M. R. Rajagopal: Providing palliative care in resource-poor countries
2.4: Neil Macdonald: IAHPC list of the essential medicines for palliative care
Section 3: The challenge of palliative medicine
3.1: Nathan I. Cherny: The problem of suffering and the principles of assessment in palliative medicine
3.2: Jane Ingham, Meg Sands & Michael Piza: The epidemiology of death and symptoms
3.3: Paul Glare, Christian Sinclair, Michael Downing & Patrick Stone: Predicting survival in patients with advanced disease
3.4: Raphael Catane & Nathan Cherny: Palliative medicine and modern cancer care
3.5: Fiona Graham, Suresh Kumar & David Clark: Barriers to the delivery of palliative care
3.6: Karen Steinhauser & James Tulsky: Defining a good death
3.7: Jonathan Koffman & LaVera Crawley: Cultural aspects of palliative medicine
3.8: Thomas Smith & J Brian Cassel: The economic challenges of palliative medicine
Section 4: The interdisciplinary team
4.1: Dagny Faksvåg Haugen, Friedemann Nauck & Augusto Caraceni: The core team and the extended team
4.2: Deborah Witt Sherman: Nursing and palliative care
4.3: Barbara Monroe: Social work in palliative care
4.4: Rev. James M. Harper, III & Rabbi Jonathan E. Rudnick: The role of the chaplain in palliative care
4.5: Jennifer Miller & Jill Cooper: Occupational therapy in palliative care
4.6: Clare O'Callaghan: Music therapy in palliative care
4.7: Rosemary Richardson & Isobel Davidson: The dietician and nutritionist in palliative care
4.8: Diane Robinson & Anne English: Physiotherapy in palliative care
4.9: Alison MacDonald & Linda Armstrong: Speech and language therapy in palliative care
4.10: Michèle Wood: Art therapy in palliative care
4.11: Jane Ellen Barr: The contribution of stoma nurse specialist to palliative care
4.12: Fiona Cathcart: Clinical psychology in palliative care
4.13: Margaret Gibbs: The clinical pharmacist in palliative care
Section 5: Ethical issues
5.1: Kenneth Calman: Introduction
5.2: Ira Byock & Diane Palac: Confidentiality
5.3: Martin Tattersall: Truth-telling and consent
5.4: Vic Larcher & Dr Dilini Rajapakse: Palliative medicine in children: ethical and legal issues
5.5: Lars Johan Materstvedt & Dr Georg Bosshard: Euthanasia and physician-assisted suicide
5.6: Joe Fins & Elizabeth Nilson: Withholding and withdrawing life-sustaining therapy
Section 6: Communication and palliative medicine
6.1: Lesley Fallowfield: Communication with the patient and family in palliative medicine
6.2: Anna C. Muriel & Paula K. Rauch: Talking with families and children about the death of a parent
6.3: David Jeffrey: Communication with professionals
6.4: Kenneth Calman: Communication with the public, policy makers and the media
Section 7: Research in palliative medicine
7.1: Geoffrey Hanks & Stein Kaasa: Research in palliative care: getting started
7.2: Henry J. McQuay, Andrew Moore & Philip Wiffen: The principles of evidence-based medicine
7.3: John Farrar: Clinical trials in palliative care
7.4: Linda J. Kristjanson & Nessa Coyle: Qualitative research
7.5: David W. Kissane, Annette F. Street & Erin Schweers: Research into psychosocial issues
7.6: David Casarett: Ethical issues in palliative care research
7.7: Jane Ingham, Russ Portenoy & Anthoulla Mohamudally: Measurement of pain and other symptoms
7.8: Stein Kaasa & John Havard Loge: Quality of life measurement in palliative medicine - principles and practice
7.9: Keela Herr & Mary Ersek: Measurement of pain and other symptoms in the cognitively impaired
7.10: Irene J. Higginson: Clinical and organisational audit and quality improvement in palliative medicine
Section 8: Principles of drug use in palliative medicine
8.1: Geoffrey Hanks: Principles of drug use in palliative medicine
Section 9: Disease modifying management in advanced cancer
9.1: Malcolm McIllmurray: The medical treatment of cancer in palliative care
9.2: Peter J. Hoskin: Radiotherapy in symptom management
9.3: Robert Krouse: The role of general surgery in the palliative care of patients with cancer
9.4: John Healey & Wakenda Tyler: The role of orthopaedic surgery in the palliative care of patients with cancer
9.5: Tarun Sabharwal, N Fotiadis & Andy Adam: The role of interventional radiology in the palliative care of patients with cancer
Section 10: The management of Common Symptoms and Disorders
10.1: The management of pain
10.1.1: Gordon Williams & Tony Dickenson: Pathophysiology of pain in cancer and other terminal diseases
10.1.2: Nathan I Cherny: Pain assessment and cancer pain syndromes
10.1.3: Nanna Brix Finnerup & Troels Staehelin Jensen: Neuropathic pain
10.1.4: Lesley A Colvin & Marie Fallon: Cancer induced bone pain
10.1.5: Giovambattista Zeppetella: Breakthrough pain
10.1.6: Geoffrey Hanks, Nathan Cherny & Marie Fallon: Opioid analgesic therapy
10.1.7: Per Sjøgren, Frank Elsner & Stein Kaasa: Non-opioid analgesics
10.1.8: David Lussier & Russell Portenoy: Adjuvant analgesics in pain management
10.1.9: Robert A. Swarm, Menelaos Karanikolas & Michael J. Cousins: Injections, neural blockade, and implant therapies for pain control
10.1.10: Nicholas Park & Nik Patel: The role of surgical neuroablation for pain control
10.1.11: Michaela Bercowitz & Nathan I. Cherny: Treating pain with transcutaneous electrical nerve stimulation
10.1.12: Jacqueline Filshie & John W. Thompson: Acupuncture
10.1.13: William Breitbart, Steven D. Passik & David Casper: Psychological and psychiatric interventions in pain control
10.2 Gastro-intestinal symptoms
10.2.1: Kathryn A. Mannix: Palliation of nausea and vomiting
10.2.2: Claud Regnard: Dysphagia, dyspepsia and hiccup
10.2.3: Nigel Sykes: Constipation and diarrhoea
10.2.4: Carla Ripamonti & Sebastian Mercadante: Pathophysiology and management of malignant bowel obstruction
10.2.5: Jeremy Keen: Jaundice, ascites and hepatic encephalopathy
10.3 Weight loss in palliative medicine
10.3.1: Florian Strasser & Vickie Baracos: Classification and pathophysiology of the anorexia/cachexia syndrome
10.3.2: Ken Fearon, Vickie Baracos & Sharon Watanabe: Classification, clinical assessment and treatment of the anorexia-cachexia syndrome.
10.4 Fatigue and asthenia
10.4: Sriram Yennurajalingam & Eduardo Bruera: Fatigue and asthenia
10.5 Clinical management of anaemia, cytopenias and thrombosis in palliative medicine
10.5: Robert Turner: Clinical management of anaemia, cytopenias and thrombosis in palliative medicine
10.6 Pruritus and sweating in palliative medicine
10.6: Mark R. Pittelkow & Charles L. Loprinzi: Pruritus and sweating in palliative medicine
10.7 Skin problems in palliative medicine
10.7.1: Michal Lotem: Medical aspects
10.7.2: Patricia Grocott & Vicky Robinson: Nursing aspects
10.7.3: Vaughan Keeley: Lymphoedema
10.8 Genito-urinary problems in palliative medicine
10.8: Richard W. Norman & Greg Bailly: Genito-urinary problems in palliative medicine
10.9 Mouth care
10.9: Franco De Conno, Cinzia Martini, Alberto Sbanotto, Carla Ripamonti & Vittorio Ventafridda: Mouth care
10.10 Endocrine and metabolic complications of advanced cancer
10.10: Mark Bower & Sarah Cox: Endocrine and metabolic complications of advanced cancer
10.11 Neurological problems in advanced cancer
10.11: Augusto Caraceni, Cinzia Martini & Fabio Simonetti: Neurological problems in advanced cancer
10.12 Sleep in palliative care
10.12: Michael J. Sateia & Ira Byock: Sleep in palliative care
10.13 Withdrawing life support - clinical advice for challenging scenarios
10.13: Gordon D. Rubenfeld: Withdrawing life support - clinical advice for challenging scenarios
10.14 Clinical management of bleeding complications
10.14: Jose Pereira & Sophie Pautex: Clinical management of bleeding complications
Section 11: Issues in specific neoplastic disease
11.1: Kin-Sang Chan, Doris M.W. Tse, Michael M.K. Sham & Anne Berit Thorsen: Palliative medicine in malignant respiratory diseases
11.2: Barbara A. Murphy, Anthony Cmelak, Steven Bayles, Ellie Dowling, Cheryl R Billante, Sheila Ridner, Kirsten Hamean, Stewart Bond, Anne Marie Flores & Wisawatapnimit Panarut: Head and neck cancer
11.3: Claudia Bausewein, Gian Domenico Borasio & Raymond Voltz: Brain tumours
Section 12: Palliative medicine in non-malignant disease
12.1: Marie Fallon: Introduction
12.2: Roger Woodruff & David Cameron: AIDS in adults
12.3: Richard M. Leach: Palliative medicine and non-malignant, end-stage respiratory disease
12.4: Andrew D. McGavigan, Francis G. Dunn & Carolyn Datta: Palliative medicine for patients with end-stage heart disease
12.5: G.D. Borasio, A. Rogers, S. Lorenzl & R. Voltz: Palliative medicine in non-malignant neurological disorders
12.6: Jo Chambers: Palliative medicine in end-stage renal failure
12.7: Simon Cohen & Thomas J. Prendergast: Palliative medicine in intensive care
Section 13: Paediatric palliative medicine
13.1: Betty Davies & Harold Siden: Special consideration for children in palliative medicine
13.2: Stephen C. Brown & Patricia A. McGrath: Paediatric pain control
13.3: John J. Collins: Symptom control in life-threatening illness in children
13.4: Michael M. Stevens: Psychological adaptation of the dying child
13.5: Betty Davies & Stacy Orloff: Bereavement issues and staff support when caring for children
Section 14: Geriatric palliative medicine
14.1: Ladislav Volicer: Palliative medicine in dementia
14.2: Diane E. Meier & Nathan Goldstein: Palliative medicine and care of the elderly
Section 15: Psychiatric, psychosocial and spiritual issues in palliative medicine
15.1: Susan McClement & Harvey Chochinov: Sprititual issues in palliative medicine
15.2: Mary L.S. Vachon: The emotional problems of the patient in palliative medicine
15.3: Joan T. Panke & Betty R. Ferrell: The family perspective
15.4: Liz Jamieson, Emma Teasdale, Alison Richardson & Amanda Ramirez: The stress of professional caregivers
15.5: William Breitbart: Psychiatric symptoms in palliative medicine
15.6: David W. Kissane & Talia Zaider: Bereavement
Section 16: Rehabilitation in palliative medicine
16.1: Deborah Franklin & Andrea Cheville: Rehabilitation in palliative medicine
Section 17: Complementary therapies in palliative medicine
17.1: Gary Deng & Barrie R. Cassileth: Complementary therapies in palliative medicine
Section 18: Palliative medicine in the home
18.1: Derek Doyle: Palliative medicine in the home: an overview
18.2: S. Lawrence Librach: Palliative medicine in the home: North America
Section 19: The terminal phase
19.1: Mike Harlos: The terminal phase
19.2: Eric Krakauer & Thomas Quinn: Sedation in palliative medicine
Section 20: Education and training in palliative medicine
20.1: Kenneth Calman: Introduction
20.2: Meg Hegarty & David Currow: Postgraduate education in palliative medicine
20.3: Charles von Gunten, Barry Buckholz & Frank Ferris: Training specialists in palliative medicine
20.4: Deborah Kirklin: The role of the humanities in palliative medicine
20.5: Jose Pereira: Informatics and palliative medicine

About the Author

Geoffrey Hanks (deceased) graduated from University College London with a BSc in anatomy and qualified in medicine in 1970. He worked in palliative medicine from 1979, initially as a research fellow with Robert Twycross in Oxford. For almost 10 years he was consultant physician in charge of the palliative care units at the Royal Marsden Hospitals, London and Sutton, and honorary senior lecturer at the Institute of Cancer Research, University of London, and St
Bartholomew's Hospital Department of Clinical Pharmacology. He was appointed to the first Chair of Palliative Medicine in the UK in the United Medical and Dental Schools of Guys and St Thomas' Hospitals, University of London, and was appointed Professor of Palliative Medicine in the University of Bristol
in 1993. Positions held include Chairman of the Palliative Care Clinical Studies Development Group of the National Cancer Research Institute in the UK and Chairman of the National NHS Cancer Research & Development Commissioning Group.
Nathan Cherny is an Australian born, Israeli oncologist and palliative medicine physician. He holds the Norman Levan Chair of Humanistic Medicine at Shaare Zedek Medical Center in Jerusalem Israel. Prof Cherny graduated in medicine at Monash University Medical School in 1983 and then completed a Fellowship of the Royal Australian College of Physicians attaining specialist recognition in both Oncology and Palliative Medicine. He subsequently completed a fellowship in Cancer Pain and Palliative
Medicine at Memorial Sloan Kettering Cancer Center. In 1994 Dr Cherny moved to Israel where he helped establish the Oncology and Palliative Medicine Unit at the Shaare Zedek Hospital in Jerusalem. He continues to head that Cancer Pain and Palliative Medicine Service, and, in addition, he continues to
practice general oncology. Since 2008 he has been the chairman or the ESMO Palliative Care Working Group.
Stein Kaasa is considered to be the leading figure in European palliative care. He is a specialist in medical oncology, radiotherapy, and palliative medicine. Since 1993, he has been the Director of the Palliative Medicine Unit at Trondheim University Hospital, Norway, and Professor of Palliative medicine at the Faculty of Medicine, Norwegian University of Science and Technology (NTNU). He is also chairman of the Unit for Applied Clinical Research and the Institute of Environmental Medicine at
NTNU, and Chairman of the Program for Research on Alternative Medicine of the Norwegian Research Council. He was responsible for the development of the core curriculum at the medical school of the NTNU. He is the current President of the European Association for Palliative Care (EAPC) and serves on
the editorial board of several journals including Progress in Palliative Care, Palliative Medicine, and the Journal of Pain and Symptom Management.
Russell Portenoy is Chairman of the Department of Pain Medicine and Palliative Care, and the Gerald J. and Dorothy R. Friedman Chair in Pain Medicine and Palliative Care at Beth Israel Medical Center in New York. He is Chief Medical Officer of Beth Israel's Continuum Hospice Care/The Jacob Perlow Hospice, and Professor of Neurology and Anesthesiology at the Albert Einstein College of Medicine. Dr. Portenoy is president of the American Academy of Hospice and Palliative Medicine and a past
president of the American Pain Society. He is the recipient of the Wilbert Fordyce Award for Lifetime Excellence in Clinical Investigation and the Distinguished Service Award from the American Pain Society, the Founder's Award from the American Academy of Pain Medicine, and the Bonica Award from the
Eastern Pain Association. He serves on the Board of Directors of the American Pain Foundation and chairs various other forums and committees.
Nicholas A. Christakis is an internist and social scientist who conducts research on social factors that affect health, health care, and longevity. He is a Professor of Medical Sociology in the Department of Health Care Policy at Harvard Medical School; Professor of Sociology in the Department of Sociology in the Harvard Faculty of Arts and Sciences; and an Attending Physician in the Department of Medicine at the Harvard-affiliated Mt. Auburn Hospital. Dr. Christakis received his BS from Yale
University in 1984, his MD from Harvard Medical School and his MPH from the Harvard School of Public Health in 1989, and his PhD from the University of Pennsylvania in 1995. He was elected to the Institute of Medicine of the National Academy of Sciences in 2006. His current research focuses on health
and social networks, and specifically how ill health, disability, health behavior, health care, and death in one person can influence the same phenomena in others in a person's social network.
Marie Fallon completed her Palliative Medicine Higher Specialist Training at St Thomas' Hospital London and in Bristol and was appointed to the St Columba's Hospice Chair of Palliative Medicine at the University of Edinburgh in 2006. She is based in the Edinburgh Cancer Research Centre and the Western General Hospital, Edinburgh. Her research background is in opioid analgesia, complex cancer pain and barriers to symptom control. She is a founder member of the University of Edinburgh's
Translational Research in Pain Group, which has a particular interest in cancer-induced bone pain. She is the Chief Investigator on a portfolio of Cancer Research UK funded multi-centre trials investigating various aspects of cancer pain. She leads a team of several Research Fellows working on various aspects
of cancer-induced bone pain. She is a member of the Advisory Board for Dimbleby Cancer Care and chairs the Pain Sub Committee of the NCRI Palliative Care Clinical Studies Group.

Reviews

A developing specialty requires a reference textbook that develops with it, and the Oxford Textbook of Palliative Medicine is just that. Its fourth edition demonstrates the textbook's responsiveness to changing times and an emerging evidence base, capturing the multidisciplinary aspects of palliative care well with its wide editorship - comprised of key clinicians in the field. European Journal on Palliative Care, Jan 2013 My opinion remains, given the presentation and the depth of coverage to be found in OTPM 4e, that it deserves its position as the gold standard in palliative medicine. IAHPC Ever since the first edition in 1993, [Oxford Textbook of Palliative Medicine] has been the reference work in the field. There is little doubt that this new edition consolidates its position as the standard work in palliative medicine. Tidsskrift for Den norske legeforening