Table of Contents

1 Front Matter; 2 Introduction; 3 1 Regulatory and Ethical Considerations; 4 2 Protocol-Development Strategies; 5 3 General Animal-Care Concerns; 6 4 Survival Studies; 7 5 Prolonged Nonsurvival Studies; 8 6 Studies of Neural Injury and Disease; 9 7 Perinatal Studies; 10 8 Agents and Treatments; 11 9 Behavioral Studies; 12 References; 13 Appendix A: Sample Size Determination; 14 Appendix B: Estimating Animal Numbers; 15 Appendix C: Biographical Sketches of Authoring Committee; 16 Index

About the Author

Committee on Guidelines for the Use of Animals in Neuroscience and Behavioral Research, National Research Council