Table of Contents

Clinical Strategies Bruce Chabner Preclinical aspects of Cancer Drug Discovery Ed Sausville, Paula Krosky, Melinda Hollingshead, Robert Shoemaker Pharmacokinetics Jerry Collins Infertility Angela Bradbury, Richard Schilsky Carcinogenesis Larry Blaszkowsky Antifolates Carmen Allegra, Brian Monahan Five Fluoropyrimidine Jean Grem Cytidine Analogues David Ryan Purine Analogues Kenneth Hande Hydroxyurea Bruce Chabner Antimicrotuble Agents Eric Rowinsky Alkylating Agents / Clinical & High Dose Roy Jones, Ken Tew Nonclassical Agents Henry Friedman Platinum Analogues Ed Reed Bleomycin Bruce Chabner Antibiotics Kees Nooter, Jaap Verweij, Edwin Willems Topo I: Inhibitors Alex Sparreboom, William Zamboni Topo II: Anthracyclines Jim Doroshow Topo II: Epipodophylotoxins Yves Pommier, Francios Goldwasser L-Asparaginase Bruce Chabner Pharmacology of CNS Agents Jeff Supko FDA Approval Thomas Roberts Catheter and Complications David Kuter, Rachel Rosovsky Pharmacogenetics Robert Diasio, Jeanne Fourie New Agents Louise Grochow Bisphosphonates Matthew Smith Thalidomide Paul Richardson Inhibitors of Tumor Angiogenesis William Gradishar, Anaadriana Zakarija Proteosome Inhibitors Owen O'Connor Molecular Targeted Drugs - Growth Factor Receptor Inhibitors Jeff Clark Monoclonal Antibody Therapies David Scheinberg Interferon Danield Linder, Earnest Borden Adoptive Therapies Carl June Vaccines Glenn Dranoff Hematopoietic Growth Factors William Petros Interleukins Gheath Alatrash, Ronald Bukowski, James Finke, Charles Tannenbaum Hormonal Therapy for Breast Cancer and Prostate Peter Lebowitz, Sandra Swain, Steven Balk

Reviews

New England Journal of Medicine, Volume 18, Issue 355 -- "The editors have taken on the Herculean task of melding chemotherapy and biologic therapy, with an emphasis on clinical relevance. To a great degree, they have accomplished their goal. The chapters are up to date, considering the rapid changes in the field. There is extensive use of illustrations and tables, and summary tables in each chapter reinforce the central themes. The discussion of antibody therapy provides an excellent overview of the current state of functional mechanisms. This textbook will continue to be a resource for clinical oncologists, and it remains one of the essential readings for medical oncologists in training. The editors and contributors should be complimented on the results of their labors, which improve on their previous exceptional efforts."