Table of Contents

Part I An Introduction to Immunobiology and Innate Immunity
1. Basic Concepts in Immunology
2. Innate Immunity

Part II The Recognition of Antigen
3. Antigen Recognition by B-cell and T-cell Receptors
4. The Generation of Lymphocyte Antigen Receptors
5. Antigen Presentation to T Lymphocytes

Part III The Development of Mature Lymphocyte Receptor Repertoires
6. Signaling Through Immune System Receptors
7. The Development and Survival of Lymphocytes

Part IV The Adaptive Immune Response
8. T Cell-Mediated Immunity
9. The Humoral Immune Response
10. Dynamics of Adaptive Immunity
11. The Mucosal Immune System

Part V The Immune System in Health and Disease
12. Failures of Host Defense Mechanism
13. Allergy and Hypersensitivity
14. Autoimmunity and Transplantation
15. Manipulation of the Immune Response

Part VI The Origins of Immune Responses
16. Evolution of the Immune System

Appendix I Immunologists’ Toolbox
Appendix II CD Antigens
Appendix III Cytokines and their Receptors
Appendix IV Chemokines and their Receptors
Appendix V Immunological Constants

About the Author

Kenneth M. Murphy, Washington University School of Medicine, St. Louis, USA.


Paul Travers, Scottish Centre for Regenerative Medicine, UK.


Mark Walport, The Wellcome Trust, UK.

Reviews

"The field of immunology is expanding rapidly and it is a difficult task to include all aspects in a single textbook, but the authors have done a commendable job to incorporate new information on topics varying from the generation of Th17 cells to pathogen recognition receptors. One of the strongest aspects of the volume is the use of visual aides for learning....The lectures are clear, informative, and enjoyable....no matter your method of instruction, this textbook will be an outstanding learning tool."
The Quarterly Review of Biology, Volume 83, No. 4, December 2008 "The highly illustrated text in color has 5 appendices, a glossary, updated references, a detailed index and a CD-ROM. Highly recommended."
Pediatric Endocrinology Reviews, Volume 5, No. 4, June 2008 "...this is an excellent overview of immunology placed in a biological context...I am pleased to have it on my shelf and I recommend it for yours if you are interested in human immunology in the broadest context or are involved in teaching the subject...Such books that make complex content easy to understand are few and far between."
British Society of Immunology Journal, Immunology News, May 2008 Praise for the Sixth Edition: "Immunobiology is one of the most outstanding introductory texts in immunology that I have come across in recent years....The book is well written and edited with lots of tables and diagrams....Most importantly, the book is easily read and understood with each topic covered in a comprehensive manner. In addition, each chapter has a number of summaries after each key concept to help the readers digest the information. Discussion questions on the topics at the end of each chapter can form the basis of discussion and be used for review and stimulating thoughts....A very attractive feature of the book is the CD-ROM - Immunobiology Interactive. It contains an archive of all the figures in the book loaded into PowerPoint presentations so these can be inserted into presentations with ease...Furthermore, there are videos and animations...In summary, this book is a must..."
World Allergy Organization News and Notes Praise for Previous Editions: "This book provides authority, clarity, breadth and inspiration. Its high standards have blazed a trailâ€|.Go and get your own copy, and fill up that inviting white margin on every page with your own notations."
TRENDS in Immunology "One of the best general immunology textbooks availableâ€|.This book clearly sets a new standard, and should not be missed by anyone interested in the subject."
Immunology Today "This is one of the best basic immunology textbooks available. Materials are well organized and clearly presented. It is a must-have for clinicians and researchers who strive to have an understanding of basic immunology."
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