Table of Contents

Folate Chemistry and Metabolism, Barry Shane
Biochemical Role of Folate in Cellular Metabolism, Conrad Wagner
Clinical Spectrum and Diagnosis of Folate Deficiency, John Lindenbaum and Robert H. Allen
Clinical Implications of Hyperhomocysteinemia, Ralph Green and Donald W. Jacobsen
Folate Requirements and Dietary Recommendations, Lynn B. Bailey
Folate Nutrition in Lactation, Mary Frances Picciano
Folate Status of U.S. Population Groups, Howerde E. Sauberlich
The Bioavailability of Folate, Jesse F. Gregory III
Folate-Cobalamin Interactions, David G. Savage and John Lindenbaum
Nutrient Interaction of Folate and Zinc, Tsunenobu Tamura
Alcohol and Folate Interactions: Clinical Implications, Charles H. Halsted
Folate and Neural Tube Defects, John M. Scott, Donald G. Weir, and Peadar N. Kirke
Folate Status: Effects on Carcinogenesis, Joel B. Mason
Folates and Folate Antagonists in Cancer Chemotherapy, David G. Priest and Marlene A. Bunni
Folate Antagonists in Nonneoplastic Disease: Proposed Mechanisms of Efficacy and Toxicity, Sarah L. Morgan and Joseph E. Baggott
Folate and Neuropsychiatry, Teodoro Bottiglieri, Richard F. Crellin, and Edward H. Reynolds

Reviews

"The quality of this text is exceptional. The writing is very consistent throughoutEach author has presented areas of research remaining unresolved and in need of new efforts. The materials enclosed in this text serve the researcher and teacher alike provides an in-depth review of new areas of clinical interest related to folate metabolism and focuses the reader's attention on important areas of research needing to be resolved. The book is recommended for everyone who enjoys reading science at its best. "-Journal of the American College of Nutrition "reading Folate in Health and Disease is a beneficial and time-efficient way for dietetics professionals to be brought up to speed about this topic. The book reviews the basic biochemical pathways and physiologic functions of folate and provides an overview of the role of folate in neural tube defects, cancer, and cardiovascular diseasemuch has happened in recent years concerning diagnostic tests for folate deficiency and these are appropriately covered. The editor and contributing authors are outstanding researchers in their respective areas, and each chapter presents a scientific approach with in-depth information that is fully referenced. "-Journal of the American Dietetic Association