Table of Contents

ForwardBrief history of EBMT/EBMT Nurses groupWhere we are nowWhere we are goingPresident of EBMT Nurses GroupIntroduction. HSCT nursing through the ages/ the evolution of the HSCT nurseArno MankBrief history of HSCT NursingImportance of HSCT nursing Extended practice roles etc.
Chapter 1. JACIE & Quality management in HSCT – Implications for NursingChapter 2. HSCT: how does it work?What HSCT nurses need to know Different types of transplantFAQsChapter 3. Donor selectionHLA typingSelecting the right donorWhich transplant for which patient?Chapter 4. Transplant PreparationThe role of the transplant Co-ordinatorInformation and consentRole of risk assessment and comorbidity scores (HCTI/ Karnofsky/ Lansky etc)Fertility preservationWork-up/ physical assessmentVenous access devices- principles of placement and careDisease assessmentThe advocacy role of the HSCT nurseEthical dilemmasPaediatric considerationsChapter 5. Cell source and ApheresisAleksander BabicCell source: where do we get the cells from?Basics of apheresisInformation and consentHaematology in Apheresis/ mobilisation of stem cellsAdverse reactionsVascular accessDonor careQuality issuesPaediatric patients/ donors and apheresisChapter 6. Principles of Conditioning Therapy & Cell infusionChemotherapyRadiotherapyImmunotherapyCell infusion: procedures and nursing carePaediatric considerationsChapter 7. BMT settings, Infections and infection controlReverse Barrier Nursing and protective Isolation Ambulatory Care Respiratory infectiosn and administration of therapyFungal infections and administration of therapyCommon viral complicationsCMVEBV-PTLDMultiply resistant bacteria – reducing the spreadC-DiffHepatitisEmerging infections (HepE)Paediatric considerationsChapter 8. Transplantation through the generationsIntroductionBrief outline of differences between Transplantation in child and the adultSection 1: Transplanting the childPaediatric CommitteeSpecial indicationsNursing considerationsSection 2: Transplanting the Young Adult/ AHA/ AdolescentLisa McMonagleSpecial indicationsNursing considerationsDiscuss the teen as a child vs adultDiscuss development of teen cancer centresSection 3: Transplanting the adultNursing considerationsSection 4: Transplanting the older adultCorien ElhinkNursing considerationsChapter 9. Early and acute complications and the principles of HSCT Nursing CareMucositis and principles or oral careSepsis and principles of careTransfusionVODHaemorrhagic cystitisEndothelial damageChapter 10. Supportive Care of the HSCT recipientArno MankNursing assessment  - vital signs and their significance/ importanceEngraftment The role of early warning scoresAssessment tools eg oral assessment, nutritional assessmentPrinciples of nutritional support Skin careOral carePsychological carePhysiotherapy and exerciseTherapeutic interventions eg complementary therapies, music, touch, massageDischarge from inpatient careReadmissions to hospitalPaediatric considerationsChapter 11. Graft versus Host Disease (GvHD)John Murray, Jacqui StringerBrief descriptionAcute vs Chronic and other categoriesAssessment criteriaDifferential diagnosesPrinciples of treatment and careTreatments – old, new, supportive and complementaryPaediatric considerationsChapter 12. Graft versus Tumour effectMRD and what it meansChimerism testing Care of the relapsed patientEarly vs late relapseChapter 13. Graft failure and rejectionPrinciples of careDifferencesTreatment optionsPaediatric considerationsChapter 14. Late effects and long term follow-upMichelle Kenyon, John Murray, Jacqui Stringer, Diana GreenfieldPrinciples of careSurvivorship and quality of lifeInvestigations and surveillance Iron chelationImmunisationsCommon concernsManaging patient expectationPalliative carePaediatric considerationsChapter 15. Improving the patient experience through research and auditAudit Clinical TrialsWhere to get help

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About the Author

Michelle Kenyon works as the Elimination of Leukaemia Fund (ELF) Post BMT Clinical Nurse Specialist at King’s College Hospital London. She has worked for more than 25 years in the field of Haemato-oncology and Stem Cell Transplantation. Her interest in improving the patient experience of Haematopoietic Stem Cell Transplantation (HSCT) led her to write "The Seven Steps", a patient information book (2002) and subsequently the "Next Steps" (2012). Around 50,000 copies of these titles have been distributed, and are now used as the basis of informed consent for transplant recipients throughout the UK.
She studied her BSc in Cancer Nursing and MSc in Advancing Cancer Nursing Practice at King’s College London, and undertook an empirical research study exploring the use of Life-coaching in Stem Cell Transplant Survivors for her dissertation. She supports patients throughout their post-transplant recovery and has a particular interest in survivorship issues and the effects of treatment. She launched the HSCT long-term follow-up clinic at King’s College Hospital in 2014 and has found the patient insights inspiring and the overall experience highly rewarding. She is the nurse representative on the BSBMT executive, Vice Chair EBMT (UK) NAP group and is Secretary of the EBMT NG. 
Aleksandra Babic is a nurse manager, affiliate to Oncology Institute of Southern Switzerland (IOSI), in Bellinzona, as Transplant Unit Coordinator and Quality manager. She received her nurse diploma from the College Center of Professional Formation in Dubrovnik, Croatia, in 1988, and was awarded a Master's degree in Nurse Management in 2006. Until 2016 she worked as a nurse manager in apheresis unit at IEO, European Institute of Oncology in Milan and has published papers on peripheral blood stem cell collection and mobilization (i.e. R-ESHAP plus pegfilgrastim as an effective peripheral stem cell mobilization regimen for autologous stem-cell transplantation in patients with relapsed/refractory diffuse large B-cell lymphoma. Transfus Apher Sci. 2013.  Successful mobilisation of peripheral blood stem cells in children using plerixafor: a case report and review of the literature. Blood Transfus. 2013. Who should be really considered as a poor mobilizer in the plerixafor era? Transfus Apher Sci. 2012 )  and photopheresis (i.e. Efficacy of photopheresis extracorporeal procedure as single treatment for severe chronic GVHD: A case report', Transfusion and Apheresis Science, 2013). In addition, Aleksandra has presented at a number of conferences worldwide, most recently including the GIIMA 3rd National Conference, GITMO and the EBMT 2015 conference: Validation of PBSC collection within JACIE program: A multicenter evaluation. From 2016 she is also a Jacie Quality Manager Inspector.Aleksandra is the former EBMT NG President (European Blood and Marrow Transplant Society) Nurses Group, which includes more than 800 nurses in 64 countries worldwide. She is a former President of GIIMA, the Italian Nurses Group in Mobilisation and Aphaeresis, and the founder and a board member of the not-for-profit association, Nurses No Frontiers.