Table of Contents

SECTION A: Chemical Basic of Life

• Biochemical Perspective to Medicine
• Subcellular Organelles and Cell Membranes
• Amino Acids: Structure and Properties
• Proteins: Structure and Function
• Enzymology: General Concepts and Enzyme Kinetics
• Chemistry of Carbohydrates
• Chemistry of Lipids

SECTION B: General Metabolism

• Overview of Metabolism
• 9 Major Metabolic Pathways of Glucose
• Other Metabolic Pathways of Glucose
• Metabolic Pathways of Other Carbohydrates
• Metabolism of Fatty Acids
• Cholesterol and Lipoproteins
• MCFA, PUFA, Prostaglandins and Compound Lipids
• General Amino Acid Metabolism (Urea Cycle, One Carbon Metabolism)
• Simple, Hydroxy and Sulfur-containing Amino Acids (Glycine, Serine, Methionine, Cysteine)
• Acidic, Basic and Branched Chain Amino Acids, (Glutamic acid, Aspartic acid, Glutamine, Asparagine, Lysine, Arginine, Nitric Oxide, Valine, Leucine, Isoleucine)
• Aromatic Amino Acids (Phenylalanine, Tyrosine, Tryptophan, Histidine, Proline) and Amino Acidurias
• Citric Acid Cycle
• Biological Oxidation and Electron Transport Chain
• Heme Synthesis and Breakdown
• Hemoglobin (Structure, Oxygen and Carbon Dioxide Transport, Abnormal Hemoglobins)

SECTION C: Clinical and Applied Biochemistry  

• Clinical Enzymology and Biomarkers
• Regulation of Blood Glucose; Insulin and Diabetes Mellitus
• Hyperlipidemias and Cardiovascular Diseases
• Liver and Gastric Function Tests
• Kidney Function Tests
• Plasma Proteins
• Acid-base Balance and pH
• Electrolyte and Water Balance
• Body Fluids (Milk, CSF, Amniotic Fluid, Ascitic Fluid)
• Metabolic Diseases
• Free Radicals and Antioxidants
• Clinical Laboratory; Quality Control
• General Techniques for Separation, Purification and Quantitation

SECTION D: Nutrition

• Fat Soluble Vitamins (A, D, E, K)
• Water Soluble Vitamins - 1 (Thiamine, Riboflavin, Niacin, Pyridoxine, Pantothenic acid, Biotin)
• Water Soluble Vitamins - 2 (Folic acid, Vitamin B12 and Ascorbic acid)
• Mineral Metabolism and Abnormalities
• Energy Metabolism and Nutrition
• Detoxification and Biotransformation of Xenobiotics
• Environmental Pollution and Heavy Metal Poisons

SECTION E: Molecular Biology

• Nucleotides: Chemistry and Metabolism
• Deoxyribonucleic Acid: Structure and Replication
• Transcription
• Genetic Code and Translation
• Control of Gene Expression
• Recombinant DNA Technology and Gene Therapy
• Molecular Diagnostics and Genetic Techniques

SECTION F: Hormones

• Mechanisms of Action of Hormones and Signaling Molecules
• Hypothalamic and Pituitary Hormones
• Steroid Hormones
• Thyroid Hormones
• Gut Hormones
• Immunochemistry
• Biochemistry of AIDS and HIV
• Biochemistry of Cancer
• Tissue Proteins in Health and Disease
• Applications of Isotopes in Medicine
• Signal Molecules and Growth Factors

About the Author

DM Vasudevan MBBS MD FAMS FRCPath
Distinguished Professor of Biochemistry, College of Medicine, Amrita Institute of Medical Sciences,
Cochin, Kerala, India

Sreekumari S MBBS MD
Professor and Head, Department of Biochemistry, Sree Gokulam Medical College and Research Foundation, Thiruvananthapuram, Kerala, India

Kannan Vaidyanathan MBBS MD
Professor and Head, Department of Biochemistry, Pushpagiri Institute of Medical Sciences and Research Centre, Tiruvalla, Kerala, India