Table of Contents

From the contents.- Preface.- Course and Outcome of Bipolar Disorder.- Genetics of Bipolar Disorder.- Epigenetic factors in Bipolar Disorder.- Clinical Endophenotypes in Bipolar Disorder.- Animal Models for the Study of Bipolar Disorder: Endophenotype and Lesion-Based Models.- Animal Models for the Study of Bipolar Disorder: Genetic-Based Models.- The Role of the –aminergic Systems in the Pathophysiology of Bipolar Disorder.- The Role of the GABAergic and Glutamatergic Systems in the Pathophysiology of Bipolar Disorder.- The Role of Signal Transduction Pathways in the Pathophysiology of Bipolar Disorder.- The Role of Synaptic and Neural Plasticity in the Pathophysiology of Bipolar Disorder.- Mitochondrial Dysfunction and Bipolar Disorder.- Structural Neuroimaging and Neuropathological Findings in Bipolar Disorder.- Functional Neuroimaging Findings in Bipolar Disorder: A Developmental Perspective.- Sleep and Biological Rhythm Abnormalities in the Pathophysiology of Bipolar Disorder.