ForwardBrief history of EBMT/EBMT Nurses groupWhere we are nowWhere
we are goingPresident of EBMT Nurses GroupIntroduction. HSCT
nursing through the ages/ the evolution of the HSCT nurseArno
MankBrief history of HSCT NursingImportance of HSCT
nursing Extended practice roles etc.
Chapter 1. JACIE & Quality management in HSCT – Implications for
NursingChapter 2. HSCT: how does it work?What HSCT nurses need to
know Different types of transplantFAQsChapter 3. Donor
selectionHLA typingSelecting the right donorWhich transplant for
which patient?Chapter 4. Transplant PreparationThe role of the
transplant Co-ordinatorInformation and consentRole of risk
assessment and comorbidity scores (HCTI/ Karnofsky/ Lansky
etc)Fertility preservationWork-up/ physical assessmentVenous access
devices- principles of placement and careDisease assessmentThe
advocacy role of the HSCT nurseEthical dilemmasPaediatric
considerationsChapter 5. Cell source and ApheresisAleksander
BabicCell source: where do we get the cells from?Basics of
apheresisInformation and consentHaematology in Apheresis/
mobilisation of stem cellsAdverse reactionsVascular accessDonor
careQuality issuesPaediatric patients/ donors and apheresisChapter
6. Principles of Conditioning Therapy & Cell
infusionChemotherapyRadiotherapyImmunotherapyCell infusion:
procedures and nursing carePaediatric considerationsChapter 7. BMT
settings, Infections and infection controlReverse Barrier Nursing
and protective Isolation Ambulatory Care Respiratory
infectiosn and administration of therapyFungal infections and
administration of therapyCommon viral
complicationsCMVEBV-PTLDMultiply resistant bacteria – reducing the
spreadC-DiffHepatitisEmerging infections (HepE)Paediatric
considerationsChapter 8. Transplantation through the
generationsIntroductionBrief outline of differences
between Transplantation in child and the adultSection 1:
Transplanting the childPaediatric CommitteeSpecial
indicationsNursing considerationsSection 2: Transplanting the Young
Adult/ AHA/ AdolescentLisa McMonagleSpecial indicationsNursing
considerationsDiscuss the teen as a child vs adultDiscuss
development of teen cancer centresSection 3: Transplanting the
adultNursing considerationsSection 4: Transplanting the older
adultCorien ElhinkNursing considerationsChapter 9. Early and acute
complications and the principles of HSCT Nursing CareMucositis and
principles or oral careSepsis and principles of
careTransfusionVODHaemorrhagic cystitisEndothelial damageChapter
10. Supportive Care of the HSCT recipientArno MankNursing
assessment - vital signs and their significance/
importanceEngraftment The role of early warning
scoresAssessment tools eg oral assessment, nutritional
assessmentPrinciples of nutritional support Skin careOral
carePsychological carePhysiotherapy and exerciseTherapeutic
interventions eg complementary therapies, music, touch,
massageDischarge from inpatient careReadmissions to
hospitalPaediatric considerationsChapter 11. Graft versus Host
Disease (GvHD)John Murray, Jacqui StringerBrief descriptionAcute vs
Chronic and other categoriesAssessment criteriaDifferential
diagnosesPrinciples of treatment and careTreatments – old, new,
supportive and complementaryPaediatric considerationsChapter 12.
Graft versus Tumour effectMRD and what it meansChimerism
testing Care of the relapsed patientEarly vs late
relapseChapter 13. Graft failure and rejectionPrinciples of
careDifferencesTreatment optionsPaediatric considerationsChapter
14. Late effects and long term follow-upMichelle Kenyon, John
Murray, Jacqui Stringer, Diana GreenfieldPrinciples of
careSurvivorship and quality of lifeInvestigations and
surveillance Iron chelationImmunisationsCommon
concernsManaging patient expectationPalliative carePaediatric
considerationsChapter 15. Improving the patient experience through
research and auditAudit Clinical TrialsWhere to get help
This is an open access book, the electronic versions are freely accessible online.
Michelle Kenyon works as the Elimination of Leukaemia Fund (ELF)
Post BMT Clinical Nurse Specialist at King’s College Hospital
London. She has worked for more than 25 years in the field of
Haemato-oncology and Stem Cell Transplantation. Her interest in
improving the patient experience of Haematopoietic Stem Cell
Transplantation (HSCT) led her to write "The Seven Steps", a
patient information book (2002) and subsequently the "Next Steps"
(2012). Around 50,000 copies of these titles have been distributed,
and are now used as the basis of informed consent for transplant
recipients throughout the UK.
She studied her BSc in Cancer Nursing and MSc in Advancing Cancer
Nursing Practice at King’s College London, and undertook an
empirical research study exploring the use of Life-coaching in Stem
Cell Transplant Survivors for her dissertation. She supports
patients throughout their post-transplant recovery and has a
particular interest in survivorship issues and the effects of
treatment. She launched the HSCT long-term follow-up clinic at
King’s College Hospital in 2014 and has found the patient insights
inspiring and the overall experience highly rewarding. She is the
nurse representative on the BSBMT executive, Vice Chair EBMT (UK)
NAP group and is Secretary of the EBMT NG.
Aleksandra Babic is a nurse manager, affiliate to Oncology
Institute of Southern Switzerland (IOSI), in Bellinzona, as
Transplant Unit Coordinator and Quality manager. She received her
nurse diploma from the College Center of Professional Formation in
Dubrovnik, Croatia, in 1988, and was awarded a Master's degree in
Nurse Management in 2006. Until 2016 she worked as a nurse manager
in apheresis unit at IEO, European Institute of Oncology in Milan
and has published papers on peripheral blood stem cell collection
and mobilization (i.e. R-ESHAP plus pegfilgrastim as an effective
peripheral stem cell mobilization regimen for autologous stem-cell
transplantation in patients with relapsed/refractory diffuse large
B-cell lymphoma. Transfus Apher Sci. 2013. Successful
mobilisation of peripheral blood stem cells in children using
plerixafor: a case report and review of the literature. Blood
Transfus. 2013. Who should be really considered as a poor mobilizer
in the plerixafor era? Transfus Apher Sci. 2012 ) and
photopheresis (i.e. Efficacy of photopheresis extracorporeal
procedure as single treatment for severe chronic GVHD: A case
report', Transfusion and Apheresis Science, 2013). In addition,
Aleksandra has presented at a number of conferences worldwide, most
recently including the GIIMA 3rd National Conference, GITMO and the
EBMT 2015 conference: Validation of PBSC collection within JACIE
program: A multicenter evaluation. From 2016 she is also a Jacie
Quality Manager Inspector.Aleksandra is the former EBMT NG
President (European Blood and Marrow Transplant Society) Nurses
Group, which includes more than 800 nurses in 64 countries
worldwide. She is a former President of GIIMA, the Italian Nurses
Group in Mobilisation and Aphaeresis, and the founder and a board
member of the not-for-profit association, Nurses No Frontiers.
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