Table of Contents

Foreword Richard Doll
Introduction
Principles of screening I: single tests
Principles of screening II: multiple tests
Part I: Screening for Specific Disorders
Disorders principally affecting the fetus or neonate
Neural Tube defects
Down's syndrome
X-linked disorders
Tay-Sachs disease
Genetic haematological disorders
Cystic fibrosis
Phenylketonuria and other inherited metabolic defects
Congenital hypothyroidism
Congenital dislocation of the hip
Disorders affecting the mother and the fetus or neonate
Acquired haematological disorders
Fetal and neonatal haemolytic disease
Infections in the fetus and newborn infant
Maternal and fetal disorders associated with high blood pressure
Part II: Certain Procedures used in Screening
Ultrasound as an ancillary investigation in the management of pregnancy
Ultrasound scanning for congenital abnormalities
Amniocentesis and chorionic villus sampling
Fetal blood and tissue sampling
Continuous electronic fetal monitoring during labour
Part III: Wider Issues
The ethics of antenatal and neonatal screening
Conclusions

Promotional Information

^BWon the BMA Medical Book Competition 2001

Reviews

This book gathers together a large amount of data about antenatal and neonatal screening. It is easy to consult and gives a very thorough review of antenatal and neonatal methodologies and procedures. It should be of great value to anyone concerned with screening procedures. Human Genetics An epidemiologist's dream... this book is unique because it brings together such a wealth of data from so many experts that it is wonderful value for the price. BMJ This is a valuable book. A rigorous approach is taken throughout... Altogether, this book contains a wealth of information on all aspects of screening in the antenatal and perinatal period. The Lancet This is an important and useful book which should be read by persons who are more involved in applying principles of prevention of disease than treatment only. World Health Forum An extraordinary amount of thought has gone into the production of the volume... The volume is essential reading for all concerned with maternal and child health and for those responsible for the provision of health services. Early Human Development This is a book that should be on main hospital or university library shelves and many epidemiologists, obstetricians, and paediatricians will wish to have a copy at hand in their own departments. International Journal of Epidemiology It is intended and should serve as a companion to screening the mother and child for the prevention of genetic and environmental disease. American Journal of Human Genetics