Table of Contents

PART I: SEQUENCE, STRUCTURE AND EXPRESSION. Chromosome Maps. Statistical Significance in Biological Sequence Comparison. Bayesian Methods in Genomics. Statistical Approaches in Eukaryotic Gene Prediction. Comparative Genomics. Gene-Expression 1. Protein Structure. Probabilistic Models for the Study of Protein Evolution. PART II: EVOLUTIONARY GENETICS. Adaptive Molecular Evolution. Genome Evolution. Virus Evolution. Application of the Likelihood Function in Phylogenetic Analysis. Phylogenetics: Parsimony and Distance Methods. Evolutionary Quantitative Genetics. PART III: ANIMAL AND PLANT BREEDING. QTLs in Inbred Lines. Mapping Quantitative Trait Loci in Outbred Pedigrees. Inferences about Breeding Values. Marker Assisted Selection and Introgression. PART IV: POPULATION GENETICS. Mathematical Models in Population Genetics. Coalescent Theory. Inference Under the Coalescent. Linkage Disequilibrium and Recombination. Inferences from Spatial Population Genetics. Analysis of Population Subdivision. Conservation Genetics. Genetic History of the Human Species. Forensics. PART V: GENETIC EPIDEMIOLOGY. Introduction to Genetic Epidemiology. Statistical Basis of Risk Calculations: A Status Report. Linkage Analysis. Nonparametric Linkage. Population Association. The Transmission/Disequilibrium Test. Pharmacogenetics. PART VI: APPLICATIONS. Ethics in the Use of Statistics in Genetics

About the Author

D. J. Balding has been one of the most prolific and influential authors of the last decade in the field of statistical interpretation of forensic DNA evidence.

M. Bishop, UK HGMP Resource Centre, Cambridge, UK.

Reviews

"Is it worth it? The answer is yes..." (Journal of Genetics, April 2006) "...sure to become the standard reference for students and researchers in all fields of statistical genetics...one of those rare commodities, an edited volume whose intellectual value may actually increase with time..." (Heredity, 2003)