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Inferring Phylogenies
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Table of Contents

1. Parsimony methods

2. Counting evolutionary changes

3. How many trees are there?

4. Finding the best tree by heuristic search

5. Finding the best tree by branch and bound

6. Ancestral states and branch lengths

7. Variants of parsimony

8. Compatibility

9. Statistical properties of parsimony

10. A digression on history and philosophy

11. Distance matrix methods

12. Quartets of species

13. Models of DNA evolution

14. Models of protein evolution

15. Restriction sites, RAPDs, AFLPs, and microsatellites

16. Likelihood methods

17. Hadamard methods

18. Bayesian inference of phylogenies

19. Testing models, trees, and clocks

20. Bootstrap, jackknife, and permutation tests

21. Paired-sites tests

22. Invariants

23. Brownian motion and gene frequencies

24. Quantitative characters

25. Comparative methods

26. Coalescent trees

27. Likelihood calculations on coalescents

28. Coalescents and species trees

29. Alignment, gene families, and genomics

30. Consensus trees and distances between trees

31. Biogeography, hosts, and parasites

32. Phylogenies and paleontology

33. Tests based on tree shape

34. Drawing trees

35. Phylogeny software

About the Author

Joe Felsenstein is Professor in the Department of Genome Sciences at the University of Washington, Seattle, where he has taught for more than thirty years. He earned a B.S. (Honors) in Zoology from the University of Wisconsin, Madison, and a Ph.D. in Zoology from the University of Chicago. Dr. Felsenstein is the author of the widely used PHYLIP package of programs for inferring phylogenies. He served as President of the Society for the Study of
Evolution in 1993 and has received numerous awards, including: election to membership in the American Academy of Arts and Sciences (1992); the Sewall Wright Award, American Society of Naturalists (1993; election to
membership in the National Academy of Sciences (1999); and the Weldon Memorial Prize, Oxford University (2000). His work has ranged from theoretical evolutionary genetics to statistical methods for inferring phylogenies. His current research interests include the development of coalescent-based Markov Chain Monte Carlo methods of computing likelihoods for models of evolution within species, and development of statistical methods for inferences about quantitative characters within and between
species.

Reviews

"Joe Felsenstein has had more positive influence on the statistical revolution of phylogenetics than any other researcher in the field. For that reason, many biologists view him as the father of statistical phylogenetics. It was with this in mind that I finally got my hands on his long-awaited book, Inferring Phylogenies. The short answer is: it delivers. Inferring Phylogenies is quite simply an instant classic."--AJ Drummond, Heredity
"The book is full of expert insights, as one would expect from an author who has made important original contributions to many of the areas he covers. Felsenstein provides beautiful and creative accounts of many topics. It will be a long time before there will be a comparable book; perhaps the field is now growing too fast for there to ever be one. The publication of Inferring Phylogenies is a milestone for evolutionary biology in general and
phylogenetics in particular."--Fredrik Ronquist, Science
"The author certainly sets out with an ambitious goal: to survey, in one book, the field of phylogenetics since computational methods entered the arena forty years ago, and he amply delivers on this promise. For researchers new to this area, the book describes contemporary methodology in a way that is both accessible and authoritative. For 'old hands,' it provides a wealth of background and commentary."--Mike Steel, TRENDS in Ecology and Evolution
"Occasionally a book is a classic by the time it is published, and this is it. The breadth is very wide with all the main expected topics. It is hard to imagine how any lab could function without this book."--David Penny, Systematic Biology
"Felsenstein's book represents a truly majestic discussion of the inference and applications of phylogenetic trees. The power of this volume lies in its unique combination of an accessible style with undoubted intellectual authority. Over 30 years ago Crow and Kimura produced what has become the cornerstone of theoretical population genetics. Felsenstein has now given us the definitive resource for anyone interested in phylogenetics. This volume is an
outstanding achievement."--Edward C. Holmes, The Quarterly Review of Biology

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