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This volume of Advances in Pharmacology is an overview of the fast-moving field of purinergic signaling through adenosine and ATP receptors

Table of Contents

The structure of the adenosine receptors: implications for drug discovery
J. Robert Lane, Veli-Pekka Jaakola, Adriaan P. IJzerman

Adenosine Receptors in Health and Disease
Stefania Gessi, Stefania Merighi, Katia Varani, and Pier Andrea Borea

Adenosine and the Regulation of Metabolism and Body Temperature
Bertil Fredholm, Stina M. Johansson and Ying-Qing Wang

Regulation of Leukocyte Function by Adenosine Receptors
Joel Linden

Role of Adenosine A2B Receptors in Inflammation
Igor Feoktistov and Italo Biaggioni

Interplay of Hypoxia and A2B Adenosine Receptors in Tissue Protection
Michael Koeppen, Tobias Eckle, and Holger Eltzschig

Allosteric Modulation of Purine and Pyrimidine Receptors
Kenneth Jacobson, Zhan-Guo Gao, Aniko Göblyös, and Adriaan IJzerman

Molecular Mechanisms of Purine and Pyrimidine Nucleotide Release
Eduardo R. Lazarowski, Juliana I. Sesma, Lucia Seminario-Vidal, and Silvia M. Kreda

Impact of Ectoenzymes on Purinergic Signalling
Filip Kukulski, Sébastien A. Lévesque, and Jean Sévigny

Ectonucleotidases as Regulators of Purinergic Signaling in Inflammation and Thrombosis
Simon C. Robson and Silvia Deaglio

P2X Receptors in Health and Disease
Geoffrey Burnstock and Charles Kennedy

Molecular Pharmacology, Physiology, and Structure of the P2Y Receptors
Ivar von Kügelgen and T. Kendall Harden2

P2Y Receptors in Health and Disease
David Erlinge

P2 Receptor Signaling in Neurons and Glia of the Central Nervous System
Laszlo Köles Anna Leichsenring, Patrizia Rubini and Peter Illes

Role of Purinergic Receptors in Neuroprotection

Tozaki-Saitoh Hidetoshi, Makoto Tsuda, and Kazuhide Inoue