A Historical Perspective.The Albumin Molecule: Its Structure and Chemical Properties.Ligand Binding by Albumin.Genetics: The Albumin Gene.Metabolism: Albumin in the Body.Clinical Aspects: Albumin in Medicine.Practical Aspects: Albumin in the Laboratory.Subject Index.
Key Features
* Includes up-to-date sequences, structures, and compositions of
many species
* Reviews the protein chemistry, genetic control, and metabolism of
albumin
* Covers medical and cell culture applications in vivo and in
vitro, with a section on handling albumin in the laboratory
* Presents the relationship of albumin to its superfamily with an
updated scheme for their evolution
* First complete coverage of all aspects of serum albumin in one
volume, with more than 2000 references
"Ted Peters brings these diverse aspects of the proteins
fascination together with a relaxed style in this definitive volume
on albumin and its homologues... The huge ensuing literature has
been expertly distilled into an understandable account of its
binding properties, which are interpreted in the context of the
three-dimensional structure, recently determined by Carter and
colleagues. The heart shape and heart of the molecule is exposed in
a number of elegant colour plates, andresidues involved in binding
are clearly displayed in a reconfiguration of the familiar
disulphide-bonded model. The student of molecular genetics and
protein evolution will find a clear interpretation of the
relationships... There is also an up-to-the minute account of human
albumin mutations... No aspects of albumin synthesis, secretion,
circulatory modification and ultimate degradation have escaped
attention, and neither has its clinical relevance in health and
disease... Ted Peters has spent a lifetime studying this protein
and his personal insights into what makes it tick will benefit all
who might use or abuse it. All About Albumin is unlikely to spend
much time on the library shelf; its hands-on approach will ensure
its place in the clinical laboratory and on the researchers desk."
--Stephen O. Brennan, School of Medicine, Christchurch, New
Zealand, in TIBS
"The author met his objectives admirably. The book is clearly
written with chapters on structure, ligand binding, genetics,
metabolism, clinical aspects, and practical aspects, i.e.,
laboratory procedures. There is a reference list of approximately
2000 entries, with the latest entries from 1994... This volume is
an admirable work of excellent quality and wide usefulness. It
should be on the shelves of every institutional library and in the
personal library of anyone who is working with or has an interest
in serum albumin." --DOODY'S HEALTH SCIENCES JOURNAL
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