Table of Contents

1. The Concept of neuroglia: a historical perspective; PART 1: PROPERTIES OF NEUROGLIAL CELLS; Morphology and ultrastructure of glial cells; 2. Astrocytes and ependymal glia; 3. Structure and function of oligodentrocytes; 4. Schwann cells and myelin; 5. Microglial cells; Lineage; 6. Lineages of astrocytes and oligodendrocytes; 7. The Schwann cell lineage; 8. The role of neurogenic astroglial cells in the developing and adult central nervous system; Physiological and biochemical properties; 9. Voltage-activated ion channels in glial cells; 10. Receptors for neurotransmitters and hormones; 11. Cytokine and chemokine receptors and signalling; 12. Mechanisms of solute transport in glia; 13. Gap junctions and hemichannels; 14. Quantal release of transmitter: not only from neurons but from astrocytes as well?; 15. Enzymes of carbohydrate and energy metabolism; 16. Second messenger systems; 17. Intracellular calcium control mechanisms in glia; 18. Cytoskeletal proteins in astroglia; PART 2: FUNCTIONS OF NEUROGLIAL CELLS; Myelin; 19. Molecular biology of myelination; 20. Factors controlling myelin formation; 21. Myelin function and saltatory conduction; Immune function; 22. Cytokine production; 23. Interaction of glial cells with monocytes; 24. Antigen processing, presentation, and T cell interaction; Blood-brain-barrier; 25. The role of glia in the formation and function of the blood-brain-barrier; Influence on neurons; 26. Extracellular potassium and pH: homeostasis and signalling; 27. Astrocyte neurotransmitter uptake; 28. Glia and synaptic transmission; 29. The central role of astrocytes in neuroenergetics; 30. Growth factors for neurons provided by macroglial cells; Development; 31. Radial glial cells: scaffolding for cortical development and evolution; 32. Axon guidance; PART 3: DISEASE AND NEUROGLIAL CELLS; Mechanisms of glial injury; 33. Astrocyte injury; 34. Oligodendrocyte and Schwann cell injury; 35. Response of microglia to brain injury; Recovery of neural function; 36. Axonal regeneration in the peripheral nervous system of mammals; 37. Axonal regeneration in the central nervous system of mammals; 38. Transplantation of myelin-forming cells; Diseases; 39. Multiple Sclerosis; 40. Human immunodeficiency virus infection of the central nervous system; 41. Focal cerebral ischemia: the multifaceted role of glial cells; 42. Gliomas; 43. Neurological mouse mutants: a molecular-genetic analysis of myelin proteins; 44. Astrocytic swelling in neuropathology; 45. The activation of microglia as an early sign of disease progression in Alzheimer's disease; 46. Peripheral neuropathy and the Schwann cell; 47. Reaction of glial cells in infectious disorders of the central nervous system

Reviews

The book is unquestionably an authoritative and comprehensive compilation of the various aspects on neuroglia. Journal of Chemical Neuroanatomy, Vol 31 ... I very much like this new edition of Neuroglia. it is a wonderful book focused entirely on glial cells ... [it is] without doubt the best place to turn to for some glial education ... All in all, Kettenmann and Ransom have once again done a great job of putting together this terrific book ... Nature Neuroscience