Table of Contents

Preface
Part I. Introduction
1: Stephen C. Stearns, Randolph M. Nesse, and David Haig: Introducing evolutionary thinking for medicine
Part II. The history and variation of human genes
2: Jean-François Guégan, Franck Prugnolle, and Frédéric Thomas: Global spatial patterns of infectious diseases and human evolution
3: Diddahally R. Govindaraju and Lynn B. Jorde: Medically relevant variation in the human genome
4: Michael Bamshad and Arno G. Motulsky: Health consequences of ecogenetic variation
5: Kenneth K. Kidd and Judith R. Kidd: Human genetic variation of medical significance
Part III. Natural selection and evolutionary conflicts
6: David Haig: Intimate relations: evolutionary conflicts of pregnancy and childhood
7: Richard G. Bribiescas and Peter T. Ellison: How hormones mediate tradeoffs in human health and disease
8: Dagan A. Loisel, Susan C. Alberts, and Carole Ober: Functional significance of MHC variation in mate choice, reproductive outcome, and disease risk
9: Beverly I. Strassmann and Ruth Mace: Perspectives on human health and disease from evolutionary and behavioral ecology
Part IV. Pathogens: resistance, virulence, variation, and emergence
10: Carl T. Bergstrom and Michael Feldgarden: The ecology and evolution of antibiotic resistant bacteria
11: Andrew F. Read and Margaret J. Mackinnon: Pathogen evolution in a vaccinated world
12: Dieter Ebert and James J. Bull: The evolution and expression of virulence
13: Paul M. Sharp, Elizabeth Bailes, and Louise V. Wain: Evolutionary origins of diversity in human viruses
14: Daniel Dykhuizen and Awdhesh Kalia: The population structure of pathogenic bacteria
15: Julian Parkhill: Whole-genome analysis of pathogen evolution
16: Mark Woolhouse and Rustom Antia: Emergence of new infectious diseases
17: Jacob C. Koella and Paul Turner: Evolution of parasites
Part V. Noninfectious and degenerative disease
18: Martin Ackermann and Scott D. Pletcher: Evolutionary biology as a foundation for studying aging and aging-related disease
19: Christopher W. Kuzawa, Peter D. Gluckman, Mark A. Hanson, and Alan S. Beedle: Evolution, developmental plasticity, and metabolic disease
20: William R. Leonard: Lifestyle, diet, and disease: comparative perspectives on the determinants of chronic health risks
21: Mel Greaves: Cancer: evolutionary origins of vulnerability
22: Natalia L. Komarova and Dominik Wodarz: Cancer as a microevolutionary process
23: Steven N. Austad and Caleb E. Finch: The evolutionary context of human aging and degenerative disease
References
Index

About the Author

Professor Stearns specializes in life history evolution, which links the fields of ecology and evolutionary biology, in evolutionary medicine, and in evolutionary functional genomics. He came to Yale in 2000 from the University of Basel, Switzerland, where he had been professor of zoology since 1983 and held several administrative posts. Prior to moving to Basel he was an assistant professor in the Biology Department at Reed College in Oregon. Born in
Hawaii and a 1967 graduate of Yale College, Stearns earned a M.S. from the University of Wisconsin and a Ph.D. from the University of British Columbia. Professor Koella's interests lie in the coevolution of
parasites and hosts. He specializes in the evolutionary epidemiology of malaria and in the application of evolutionary ideas to the control of malaria. After obtaining a Masters' in mechanical engineering at the ETH Zurich and a PhD in evolutionary biology at the University of Basel he worked for several years at the Swiss Tropical Institute Basel as a malaria epidemiologist before moving on to positions in Switzerland, Denmark and France. He arrived at Imperial College in 2005 as a Chair in
Epidemiology.

Reviews

`Review from previous edition 'Provides intriguing reading.''
J.C. von Vaupel Klein, Koninklijke Brill NV, 1999
`'Evolution in Health and Disease is likely to set a benchmark for the many contributions that will certainly follow.''
Mark Pagel, Science
`'...This is a fascinating book, with contributions from many leading researchers, which should interest biologists, medics and veterinarians alike. It is the state-of-the-art text for evolutionary medicine and provides an excellent platform for the development of this important subject.''
Mark E.J. Woolhouse, Trends in Microbiology
`'...This book and others like it should help evolutionary thinking permeate medicine more rapidly''
Parasitology Today