Table of Contents

Part I: General Principles, Lynn Wecker

1 Pharmacodynamics: Receptors and Concentration-Response Relationships

2 Pharmacokinetics: Absorption, Distribution, Metabolism and Elimination

3 Clinical Pharmacokinetics and Issues in Therapeutics

4 Drug Development, Regulation and Prescription Writing

5 Gene Therapy and Emerging Molecular Therapies

6 Antibodies and Biological Products

7 Herbals and Natural Products

8 Principles of Toxicology

Part II: Drugs Affecting the Peripheral Nervous System, Skeletal and Smooth Muscle, Carl Faingold

9 Introduction to the Autonomic Nervous System

10 Drugs Affecting the Parasympathetic Nervous System and Autonomic Ganglia

11 Drugs Affecting the Sympathetic Nervous System

12 Skeletal Muscle Relaxants

13 Local Anesthetics

14 Histamine and Antihistamines

15 Eicosanoids

16 Drugs to Treat Asthma and Chronic Obstructive Pulmonary Disease

17 Drugs Affecting Uterine Motility

18 Drugs Affecting the Gastrointestinal System

Part III: Drugs Affecting the Cardiovascular, Renal and Circulatory Systems, Stephanie Watts

19 Introduction to the Regulation of Cardiovascular Function

20 Antihypertensive Drugs

21 Diuretic Drugs

22 Antiarrhythmic Drugs

23 Drugs to Treat Heart Failure

24 Vasodilators and Nitric Oxide Synthase

25 Lipid-Lowering Drugs and Atherosclerosis

26 Antithrombotic Drugs

Part IV: Drugs Affecting the Central Nervous System, Lynn Wecker

27 Introduction to the Central Nervous System

28 Treatment of Parkinson's and Alzheimer's Diseases

29 Treatment of Psychotic Disorders

30 Treatment of Affective Disorders

31 Treatment of Anxiety and Insomnia

32 Ethanol, Other Alcohols and Drugs for Alcohol Dependence

33 Treatment of Obesity and Eating Disorders

34 Treatment of Seizure Disorders

35 General Anesthetics

36 Drugs to Control Pain

37 Drugs and Substance Abuse, Addiction and Treatment

Part V: Drugs Affecting Endocrine Systems, George Dunaway

38 Introduction to Endocrine Pharmacology and Hormones of the Hypothalamus and Pituitary Gland

39 Adrenocorticosteroids

40 Estrogens and Progestins

41 Androgens and Antiandrogens

42 Thyroid and Antithyroid Drugs

43 Insulin and Drugs Used in the Therapy of Diabetes Mellitus

44 Calcium-Regulating Hormones and Other Agents Affecting Bone

Part VI: Chemotherapy of Invading Organisms, Lynn Crespo

45 Principles of Antimicrobial Use

46 Bacterial Cell Wall Synthesis Inhibitors

47 Inhibitors of Bacterial Ribosomal Actions

48 Bacterial Folate Antagonists, Fluoroquinolones, and Other Antibacterial Agents

49 Antimycobacterial Agents

50 Antifungal Agents

51 Antiviral Agents

52 Drugs to Treat Parasitic Infections

Part VII: Chemotherapy of Neoplastic Diseases, Lynn Crespo

53 Principles of Antineoplastic Drug Use

54 Mechanisms of Action of Antineoplastic Drugs

55 Adjuvant Antineoplastic Drugs

About the Author

Carl L. Faingold is an American neuroscientist who is a Distinguished Professor in the Department of Pharmacology of Southern Illinois University School of Medicine in Springfield, Illinois; he is a founding faculty member of both the department and the School of Medicine. Professor Lynn Wecker has recently retired from teaching at USF College of Medicine Tampa Florida, and has agreed to stay on for a final edition to help Susan learn the ropes.

Reviews

A recent review of: Brody's Human Pharmacology: Molecular to Clinical, 5th Edition [Excerpt from a review by Thomas L. Pazdernik, PhD (University of Kansas Medical Center), from Doody's Reviews] This is by far the best edition of this book since section editors have made certain that each chapter is current and follows the same format of therapeutic overview, mechanisms of action, pharmacokinetics, relation of mechanisms of action to clinical response, pharmacovigilance (side effects, clinical problems, and toxicity), and new horizons. The focus is on prototypic drugs with ample use of tables and boxes to provide valuable summaries of how important clinical drugs differ from the prototypic drugs described in detail. The multicolored figures are both attractive and informative. Each chapter ends with a short, relevant, up-to-date further reading list and a few self-assessment questions. The questions highlight key concepts and drugs covered in the chapter, but are not of the style or complexity of questions currently used on USMLE examinations. Excellent descriptive answers to the self-assessment questions are provided in the appendix. Buyers are also provided with a PIN number for a Student Consult web site which includes complete contents of the book online plus multiple choice questions with feedback as well as other learning enrichments. This edition is a markedly improved book that rivals Basic and Clinical Pharmacology, 10th edition, by Katzung (McGraw-Hill, 2007), as a leading pharmacology textbook for teaching pharmacology to health professionals. I highly recommend this fifth edition for adoption. Weighted Numerical Score: 94 - 4 Stars!