Table of Contents

Section 1 General aspects

1. Epidemiology of headache

2. The social impact and burden of headache

Section 2 Biological science of headache

3. Biological sciences related to headache

4. Pharmacology

5. Biological science of headache channels

6. Genetics of headaches

7. The neurobiology of migraine

8. Experimental models of migraine

Section 3 Management of headache

9. Management of headache patients

10. Headache diaries and calendars

11. Implementing the International Classification of Headache Disorders, 2nd edition (ICHD-II)

12. Triggers of migraine and tension-type headache

13. Acute headache in the emergency department

14. Therapeutic guidelines for headache

15. The role of prevention

16. Managing migraine associated with sensitization

17. Botulinum neurotoxin in the treatment of headache disorders

18. The approach to the difficult patient

19. Ethical issues in headache management

20. The role of lay associations

Section 4 Primary headache

21. Migraine: general aspects

22. Pathophysiology of migraine

23. Migraine – clinical neurophysiology

24. Migraine: clinical diagnostic criteria

25. Migraine and reproductive life

26. Acute treatment of migraine

27. Migraine: preventive treatment

28. Tension-type headache: introduction and diagnostic criteria

29. Tension-type headache: mechanisms

30. The clinical neurophysiology of tension-type headache

31. Treatment of tension-type headache

32. Cluster headache and trigeminal autonomic cephalalgias: general aspects

33. Pathophysiology of cluster headache and other trigeminal autonomic cephalalgias

34. Neuroimaging and clinical neurophysiology in cluster headache and trigeminal autonomic cephalalgias

35. Cluster headache and other trigeminal autonomic cephalalgias: diagnostic criteria

36. Acute and preventive treatment of cluster headache and other trigeminal autonomic cephalgias

37. Neurostimulation therapy in intractable headaches

38. Other primary headache – general aspects

39. Primary stabbing headache

40. Primary cough headache, primary exertional headache, and primary headache associated with sexual activity

41. Hypnic headache

42. Primary thunderclap headache

43. Hemicrania continua

44. New daily persistent headache

Section 5 Secondary headaches

45. Secondary headaches: introduction

46. Headache attributed to head or neck trauma

47. Headache attributed to stroke, TIA, intracerebral haemorrhage, or vascular malformation

48. Headache attributed to arteritis, cerebral venous thrombosis, and other vascular intracranial disturbances

49. Headache attributed to carotid or vertebral artery pain

50. Headache attributed to non-vascular intracranial disorder

51. Headache attributed to a substance or its withdrawal

52. Headache attributed to infections: nosography and differential diagnosis

53. Headache attributed to disorders of homeostasis

54. Headache or facial pain attributed to disorders of cranium, neck, eyes, ears, nose, sinuses, teeth, mouth, or other facial or cranial structures

55. Headache attributed to psychiatric disorders

56. Cranial neuralgias

57. Surgical treatment of cranial neuralgias

58. Central pain in the face and head

Section 6 Special issues

59. Chronobiological correlates of primary headaches

60. Headache: endocrinological aspects

61. Headache in children

62. Vestibular migraine

63. Pharmacological migraine provocation: a human model of migraine

64. Neuroimaging in headache

65. Current and emerging therapies for migraine prevention and treatment

Promotional Information

This volume is part of the Handbook of Clinical Neurology series, the world's most comprehensive source of information in neurology. Now in its third generation, the series has an unparalleled reputation for providing the latest foundational research, diagnosis, and treatment protocols essential for both basic neuroscience research and clinical neurology

Reviews

"This book offers a complete overview and update of the scientific and cultural developments that, since the publication of the previous Handbook on headaches, have revolutionised understanding of migraine and other headaches. This process was made possible by the fact that many of the distinguished authors who contributed to the book have been protagonists in the advancement of headache science in recent decades. The aim of the publishers of this third edition of the Handbook was to provide basic researchers and clinicians with an updated bibliographical resource that would increase all-round knowledge of the various forms of headache and also provide pointers for new lines of research. On reading this book it is clear that Professors Nappi and Moskowitz have accomplished this arduous task. The broad range of different skills and backgrounds (not only geographical but also cultural) of the editors and co-authors of this book not only provide a guarantee of its undisputed scientific quality, but also give it an international dimension."--Functional Neurology 2012; 29(1): 67