Table of Contents

Preface. Contributors. PART I: INTRODUCTION. 1. Introduction to Toxicology (Ernest Hodgson). 2. Introduction to Biochemical and Molecular Methods in Toxicology (Ernest Hodgson, Gerald A. LeBlanc, Sharon A. Meyer and Robert C. Smart). 3. Toxicant Analysis and Quality Assurance Principles (Ross B. Leidy). PART II: CLASSES OF TOXICANTS. 4. Exposure Classes, Toxicants in Air, Water, Soil, Domestic and Occupational Settings (W. Gregory Cope). 5. Classes of Toxicants: Use Classes (W. Gregory Cope, Ross B. Leidy and Ernest Hodgson). PART III: TOXICANT PROCESSING IN VIVO. 6. Absorption and Distribution of Toxicants (Ronald E. Baynes and Ernest Hodgson). 7. Metabolism of Toxicants (Randy L. Rose and Ernest Hodgson). 8. Reactive Metabolites (Randy L. Rose and Patricia E. Levi). 9. Chemical and Physiological Influences on Xenobiotic Metabolism. 10. Elimination of Toxicants (Gerald A. LeBlanc). PART IV: TOXIC ACTION . 11. Acute Toxicity (Gerald A. LeBlanc). 12. Chemical Carcinogenesis (Robert C. Smart). 13. Teratogenesis (Stacy Branch). PART V: ORGAN TOXICITY. 14. Hepatotoxicity (Ernest Hodgson and Patricia E. Levi). 15. Nephrotoxicity (Ernest Hodgson and Patricia E. Levi). 16. Toxicology of the Nervous System (Bonita L. Blake). 17. Endocrine System (Gerald A. LeBlanc). 18. Respiratory Toxicity (Ernest Hodgson, Patricia E. Levi and James C. Bonner). 19. Immunotoxicity (MaryJane Selgrade). 20. Reproductive System (Stacy Branch). PART VI: APPLIED TOXICOLOGY. 21. Toxicity Testing (Helen Cunny and Ernest Hodgson). 22. Forensic and Clinical Toxicology (Stacy Branch). 23. Prevention of Toxicity (Ernest Hodgson). 24. Human Health Risk Assessment (Ronald E. Baynes). PART VII: ENVIRONMENTAL TOXICOLOGY. 25. Analytical Methods in Toxicology (Ross B. Leidy). 26. Basics of Environmental Toxicology (Gerald A. LeBlanc). 27. Transport and Fate of Toxicants in the Environment (Damian Shea). 28. Ecological Risk Assessment (Damian Shea). PART VIII: SUMMARY. 29. Future Considerations for Environmental and Human Health (Ernest Hodgson). Glossary. Index.

About the Author

ERNEST HODGSON, PhD, has been a professor at North Carolina State University since 1961. He currently serves as the William Neal Reynolds Professor of Toxicology.

Reviews

"...a good, easy-to-read, and comprehensive reference work for all safety professionals involved in toxicology or those wishing to broaden their knowledge of the field." (Chemical Health and Safety, March-April 2005) "...a useful introductory text and the new chapters are a valuable addition to the old edition..." (The British Toxicology Society, No 27, Winter 2005) "Students and instructors in courses in environmental, veterinary, pharmacological and medical toxicology will find this an excellent modern textbook that benefits from the current writings of experts in all the key topics of modern toxicology." (Vet Human Toxicology, 46 (4) August 2004)