PART I: THE MOLECULAR DESIGN OF LIFE Biochemistry: An Evolving Science Protein Composition and Structure Exploring Proteins and Proteomes DNA, RNA and the Flow of Genetic Information Exploring Genes and Genomes Exploring Evolution and Bioinformatics Hemoglobin: Portrait of a Protein in Action Enzymes: Basic Concepts and Kinetics Catalytic Strategies Regulatory Strategies Carbohydrates Lipids and Cell Membranes Membrane Channels and Pumps Signal Transduction Pathways PART II: TRANSDUCING AND STORING ENERGY Metabolism: Basic Concepts and Design Glycolysis and Gluconeogenesis The Citric Acid Cycle Oxidative Phosphorylation The Light Reactions of Photosynthesis The Calvin Cycle and the Pentose Phosphate Pathway Glycogen Metabolism Fatty Acid Metabolism Protein Turnover and Amino Acid Catabolism PART III: SYNTHESIZING THE MOLECULES OF LIFE The Biosynthesis of Amino Acids Nucleotide Biosynthesis The Biosynthesis of Membrane Lipids and Steroids The Integration of Metabolism DNA Replication, Repair and Recombination RNA Synthesis and Processing Protein Synthesis The Control of Gene Expression PART IV: RESPONDING TO ENVIRONMENTAL CHANGES Sensory Systems The Immune System Molecular Motors Drug Development
JEREMY M. BERG is Director of the National Institute of General Medical Sciences at the National Institutes of Health, USA. He is the recipient of the American Chemical Society Award in Pure Chemistry (1994), the Eli Lilly Award for Fundamental Research in Biological Chemistry (1995), the Maryland Outstanding Young Scientist of the Year (1995) and the Harrison Howe Award (1997). JOHN L. TYMOCZKO is the Towsley Professor of Biology at Carleton College, USA, where he has taught since 1976. LUBERT STRYER is Winzer Professor of Cell Biology, Emeritus, in the School of Medicine and
'An excellent textbook which combines basic principles of biochemistry with clinical situations and pathophysiology.' - J M Land - Clinical National Hospital London 'A superby presented book - in keeping with the high standard of the previous editions. A must for all biochemistry students.' - R E Glass - Nottingham University 'The integration of evolution makes it the most exciting and revolutionary biochemistry text to appear since 1970.' - James F. Koerner, University of Minnesota 'I really like the chemical and structural approach to describing the changes in the molecules and the energetics involved.' - Paul Craig, Rochester Institute of Technology 'Another fantastic book.' - Gunnar Hansson - Gothenburg University 'An excellent textbook for students taking biochemistry. ' - P Maskrey - Northumbria University 'Nice updates, nice web resource. The organisation of some topics has improved (i.e. Glycolysis and Gluconeogenesis in the same chapter).' - Dr Lorenzo Frigerio, University of Warwick 'An excellent revision. I like the use of structures throughout.' - R C Ford - Manchester University 'Much improved - good cover of genetics and metabolism.' - A Nicolaou - Bradford University
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