Table of Contents

Section I. Genetics in Endocrinology
Chapter 1
Monogenic and Polygenic Disorders in Endocrinology
John Phillips III and Amy Potter
Chapter 2
Genetic Syndromes with Endocrinopathies
Patricia Y. Fechner

Section II. Evaluation of Endocrine Disorders in Children
Chapter 3
Diagnostic Imaging in Pediatric Endocrinology
Donald O. Corea, Aslam R. Siddiqui, and Mary K. Edwards-Brown
Chapter 4
Molecular Concepts and Techniques in Endocrinology
Constantin Polychronakos and Zubin Punthakee

Section III. Hypothalamus and Pituitary
Chapter 5
Molecular Genetics of Hypothalamic-Pituitary Axis Development
Phu V. Tran, Jesse J. Savage, Holly A. Ingraham, and Simon J. Rhodes
Chapter 6
Manifestations of Mutations in Pituitary Transcription Factors and Clinical Disorders of the Anterior Pituitary
John S. Parks and Milton R. Brown
Chapter 7
Clinical Disorders of the Posterior Pituitary
Gary L. Robertson
Chapter 8
Endocrine Issues in Survivors of Childhood Cancer
Thomas Moshang, Jr., and Stuart A. Weinzimer

Section IV. Growth
Chapter 9 Molecular Mutations in the GH-IGF Axis
Zvi Laron
Chapter 10
Physiology of the Growth Hormone--IGF Axis
Katie Woods and Ron G. Rosenfeld
Chapter 11
Clinical Aspects of Growth and Growth Disorders
Robert Rapaport and Deborah A. Bowlby
Chapter 12
Short Stature and Quality of Life: A Review of Assumptions and Evidence
David E. Sandberg, Melissa Colsman, and Linda D. Voss
Chapter 13
Turner Syndrome
Chapter 14
Endocrinopathies in Infants Who Are Small for Gestational Age
Mireya H. Garcia, Radhika H. Muzumdar, and Paul Saenger

Section V. Sexual Differentiation and Maturation
Chapter 15
Molecular Genetic Control of Sexual Differentiation
Mary M. Lee
Chapter 16
Intersex Disorders
Mary Pat Gallagher and Sharon E. Oberfield
Chapter 17
Cryptochidism
Chapter 18
Androgens and Behavior: Implications for the Treatment of Children with Disorders of Sexual Differentiation
Sheri A. Berenbaum
Chapter 19
Control of the Onset of Puberty
J. P. Bourguignon
Chapter 20
Growth Hormone, Sex Steroids and IGF-I: Metabolic Effects in Puberty and Beyond
Nelly Mauras
Chapter 21
Precocious Puberty
Peter A. Lee and James R. Kerrigan
Chapter 22
Delayed Puberty
John C. Achermann
Chapter 23
Gynecomastia
Edward O. Reiter and Glenn D. Braunstein
Chapter 24
Hyperandrogenism in Children and Adolescents
M. Belen Roldan Martin and Selma Feldman Wichtel
Chapter 25
Endocrine Disruptors and Development of the Reproductive System: A Pediatric Perspective
Katharina M. Main, Ewa Rajpert-De Meyts, Jorma Toppari, and Niels E. Skakkebaek

Section VI. Glucose Homeostasis
Chapter 26
Hypoglycemia in Infants and Children
Agneta Sunehag and Morey W. Haymond
Chapter 27
Genetics of Type 1 Diabetes
Alba Morales, Jin-Xiong She, and Desmond Schatz