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Clinical Epidemiology
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Table of Contents
PART ONE: Performing Clinical Research
Forming Research Questions.... 3
Conducting Systematic Reviews.... 15
Finding Information About the Burden of Disease.... 49
An Introduction to Performing Therapeutic Trials.... 59
The Tactics of Performing Therapeutic Trials.... 66
The Principles Behind the Tactics of Performing Therapeutic Trials.... 173
Testing Quality Improvement Interventions.... 244
Evaluating Diagnostic Tests.... 273
Determining Prognosis and Creating Clinical Decision Rules.... 323
Assessing Claims of Causation.... 356
Generating Outcome Measurements, Especially for Quality of Life.... 388
PART TWO: Becoming a Clinical Researcher
Becoming a Successful Clinician-Investigator.... 415
Preparing a Research Protocol to Improve its Chances for Success.... 429
Online Data Collection.... 440
Analyzing Data.... 446
Preparing Reports for Publication and Responding to Reviewers' Comments.... 461
Dealing with the Media.... 474
Index.... 487
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