Table of Contents

SCIENTIFIC PRINCIPLES OF CHEMOTHERAPY: Scientific Basis of Cancer Chemotherapy, James K. Schwarz / Principles of Pharmacology, Antonius A. Miller / Norton-Simon Hypothesis, Larry Norton / Drug Resistance, James Goldie / Principles of Chemotherapy, Carl E. Freter / Clinical Trials, Barbara Barrett and Jeanette Linebaugh / Hematopoietic Growth Factors, Jeffrey Crawford / Biologic Response Modifiers: Principles of Biotherapy, Howard Ozer and Carla Kurkjian ROUTES OF ADMINISTRATION: Intraventricular and Intrathecal Therapy, Victor A. Levin, Morris D. Groves, and Arthur D. Forman / Intraperitoneal Chemotherapy, Maurie Markman / Continuous Intravenous Infusion Chemotherapy, Robert W. Carlson / Intra-arterial Chemotherapy, William D. Ensminger / Perfusion Therapy, William G. Kraybill / Hematopoietic Stem Cell Transplantation, James O. Armitage MANAGEMENT OF DRUG TOXICITY: Oral Toxicity, Douglas E. Peterson / Dermatologic Toxicity, Susan K. Ailor / Extravasation, Gerald Clamon / Hypersensitivity Reactions, Clint Daniel Kingsley / Ocular Side Effects of Chemotherapy, Linda J. Burns and Mark A. Klein / Cardiotoxicity of Cancer Therapy, Justin D. Floyd and Michael C. Perry / Pulmonary Toxicity of Antineoplasic Therapy, Ramaswamy Govindan and Daniel Morgensztern / Gastrointestinal Complications of Chemotherapy, Joel Picus / Hepatotoxicity of Chemotherapy Agents, Paul D. King / Renal and Electrolyte Abnormalities Due to Chemotherapy, Irum Shahab and William P. Patterson / Neurotoxicity of Chemotherapy Agents, Frederick H. Hausheer / Vascular Toxicity of Anti-Neoplastic Agents, Donald C. Doll and Nasir Shahab / Second Malignancies after Chemotherapy, Alfred Neugut and Thomas Uldrick / Chemotherapy in Pregnancy, Donald C. Doll / Gonadal Complications and Teratogenicity of Cancer Therapy, Catherine E. Klein DRUG ADMINISTRATION: Central Venous Access for Chemotherapy, Paul Dale CURRENT THERAPY OF SPECIFIC SOLID TUMORS: Systemic Therapy for Advanced Melanoma, Clay M. Anderson / Primary and Metastatic Brain Tumors, Mark R. Gilbert / Chemotherapy of Head and Neck Cancer, Everett Vokes and Nicholas Choong / Lung Cancer, Nasser H. Hanna and Lawrence H. Einhorn / Breast Cancer, Carl G. Kardinal / Gastrointestinal Cancer, Chris Papageorgio / Endocrine Tumors, Stephen Graziano and Keith Goldstein / Chemotherapy of Genitourinary Cancers, Gary R. MacVicar, Deborah Bradley, and Maha Hussain / Gynecologic Cancer, Vince Herrin / Chemotherapy of Carcinoma of Unknown Primary Site, John D. Hainsworth and F. Anthony Greco / Chemotherapy of Bone and Soft Tissue Sarcomas, Rashmi M. Chugh, Scott M. Schuetze, and Laurence H. Baker / Chemotherapy for Pediatric Solid Tumors, Barbara Gruner CHEMOTHERAPY OF HEMATOLOGIC MALIGNANCIES: Chemotherapy of Hodgkin Lymphoma, Bruce A. Peterson / Non-Hodgkin's Lymphoma, Philip J. Bierman and James O. Armitage / Acute and Chronic Leukemias, James E. Wooldridge / Myelodysplastic Syndromes, Bruce D. Cheson / Management of Myeloproliferative Disorders and Chronic Myeloid Leukemia, Ayalew Tefferi / Chemotherapy of Multiple Myeloma and Other Plasma Cell Disorders, Nasir Shahab APPENDICES: Chemotherapeutic Drugs, Michael C. Perry and Nancy F. McKinney / Combination Chemotherapy Programs, Michael C. Perry and Scott McGee / NCI Common Toxicity Criteria, Michael C. Perry