Table of Contents

GENERAL. Introductory Remarks. Enzymes Involved in Histamine Metabolism. Assay of Histamine and Its Metabolites in the Brain. HISTAMINE RECEPTORS. H1- and H2-Receptors. The Third Histamine Receptor. MORPHOLOGY OF HISTAMINERGIC NEURONS. Morphology of Histaminergic Neurons With Histadine Decarboxylase as a Marker. The Histaminergic Neuronal System as Revealed With Antisera Against Histamine. Afferent and Efferent Fiber Connections of Histaminergic Neurons in the Rat Brain. Comparison With Dopaminergic, Noradrenergic, and Serotonergic Systems. Neurotransmitter Coexistence in the Tuberomamillary Nucleus. Development of Histaminergic Neurons. ELECTROPHYSIOLOGICAL STUDIES. Histaminergic and Histaminoceptive Neurons: Electrophysiological Studies in Vertebrates. Histamine as a Transmitter in Invertebrates: Studies of Identified Cells in Aplysia. FUNCTIONS OF HISTAMINERGIC NEURONS. Studies With a-Fluoromethylhistidine as a Probe. Histaminergic Regulation of the Neuroendocrine System. Interactions With Psychotropic Drugs. Involvement of Histamine in Circadian and Other Rhythms. Feeding Behavior. Motion Sickness. Interactions With Other Neuron Systems. Turnover of Neuronal Histamine in the Mammalian Brain and Its Changes Induced by Drugs and Observed in Disease Models. Histamine in the Retina. Comprehensive List of Effects of Centrally Administered Histamine and Related Compounds. APPENDIX: MOST RECENT ADVANCES IN THE HISTAMINERGIC NEURON SYSTEM. INDEX.