Table of Contents

1. From Sequence to Structure

2. From Structure to Function

3. Control of Protein Function

4. From Sequence to Function: Case Studies in Structual and Functional Genomics

5. Structure Determination

About the Author

Gregory A. Petsko studied chemistry and classics as an undergraduate at Princeton University before going to Oxford as a Rhodes scholar to work for his Ph.D. with David Phillips. He then pursued his interest in the mechanism of enzyme catalysis at the Massachusetts Institute of Technology, where he taught courses in chemistry and detective fiction. Currently the Director of the Rosenstiel Center at Brandeis, he has extended his research interests
to include the use of yeast genetics to study the unfolded protein response pathway, and the mechanism of action of the ABC transporter proteins.

Dagmar Ringe graduated in chemistry from Barnard College, Columbia, and took her Ph.D. in bioorganic chemistry from Boston University. She then pursued her research interest in the study of enzyme catalysis by X-ray crystallography at the Massachusetts Institute of Technology before moving to Brandeis, where she is Professor of Biochemistry and Chemistry. The principal focus of Dr. Ringe's research is structure-function relationships in enzymes of particular industrial and
pharmaceutical importance.

Reviews

"I have not encountered a book better than this one for students interested in learning more about structure-function relationships in proteins."
--B. Williams, Choice